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RESEARCH PRODUCT
Association between urinary incontinence and frailty: a systematic review and meta-analysis
N. VeroneseP. SoysalB. StubbsA. MarengoniJ. DemurtasS. MaggiM. PetrovicC. Verdejo-bravoL. AharonyJ. De CockM. S. NuotioC. PedoneJ. RifelN. Vande WalleA. VelgheA. VellaM. SolmiA. KoyanagiT. ThompsonC. BeudartO. BruyèreG. TorbahnJ. FirthL. Smith The Special Interest Group On Urinary IncontinenceEuropean Geriatric Medicine Society (Eugms) The Special Interest Group Of Systematic Reviews And Meta-analysis For Healthy Agingsubject
GerontologyLongitudinal studya systematic review and meta-analysis- EUROPEAN GERIATRIC MEDICINE cilt.9 ss.571-578 2018 [Veronese N. SOYSAL P. Stubbs B. Marengoni A. Demurtas J. Maggi S. Petrovic M. Verdejo-Bravo C. -Association between urinary incontinence and frailty]business.industryConfoundingPsychological interventionUrinary incontinenceOdds ratiomedicine.diseaseFrailty · Urinary incontinence · Meta-analysis · AgedComorbidityConfidence interval03 medical and health sciences0302 clinical medicineMeta-analysismedicine030212 general & internal medicinemedicine.symptombusiness030217 neurology & neurosurgerydescription
Purpose: Urinary incontinence (UI) and frailty are common geriatric syndromes. Although literature increasingly supports a relationship between these two conditions, no systematic review and meta-analysis has been performed on this topic. Therefore, we aimed to investigate the potential association between UI and frailty, through a meta-analytic approach. Methods: A systematic search in major databases was undertaken until 15th March 2018 for studies reporting the association between UI and frailty. The prevalence of UI in people with frailty (vs. those without) was pooled through an odds ratio (OR) and 95% confidence intervals (CIs), with a random-effects model. The other outcomes were summarized descriptively. Results: Among 828 papers, 11 articles were eligible, including 3784 participants (mean age 78.2 years; 55.1% women). The prevalence of UI was 39.1% in people with frailty and 19.4% in those without. A meta-analysis with five studies (1540 participants) demonstrated that UI was over twice as likely in frail people versus those without (OR 2.28; 95% CI 1.35–3.86; I2 = 61%). One cross-sectional study, adjusting for potential confounders and one longitudinal study confirmed that UI is significantly associated with frailty. In two cross-sectional studies, using adjusted analyses, frailty was more common in people with UI. Conclusion: Urinary incontinence is twice as common in older people with frailty compared to older people without frailty. Screening and the development of interventions for UI and frailty could prove useful for this common comorbidity. © 2018, European Geriatric Medicine Society.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-01-01 |