0000000000586749

AUTHOR

Daniele Castellucci

0000-0001-8055-721x

showing 3 related works from this author

Frequency and clinical aspects of neurological and psychiatric symptoms in patients with non-celiac wheat sensitivity

2021

Background: Non-Celiac Wheat Sensitivity (NCWS) is characterized by both intestinal and extra-intestinal symptoms. The study aims to investigate the frequency of neuropsychiatric manifestations in NCWS patients and identify their clinical and demographic characteristics. Methods: 278 clinical records of NCWS patients, diagnosed by a double-blind placebo-controlled wheat challenge between 2006 and 2020, were retrospectively revised. Fifty-two patients with Celiac Disease (CD) and 54 patients with Irritable Bowel Syndrome (IBS) served as controls. Results: 87% of the NCWS patients had an IBS-like clinical presentation. The NCWS group showed a longer duration of symptoms, a higher frequency of…

0301 basic medicineduodenal lymphocytosisAdultMalemedicine.medical_specialtyLymphocytosisnon-celiac wheat sensitivityDiseaseWheat HypersensitivityGastroenterologyArticleDuodenal lymphocytosis HLA Irritable bowel syndrome Multiple food hypersensitivity Neuropsychiatric symptoms Non-celiac wheat sensitivity Adult Celiac Disease Female Humans Irritable Bowel Syndrome Male Nervous System Diseases Wheat HypersensitivityIrritable Bowel Syndrome03 medical and health sciences0302 clinical medicineInternal medicinemedicineIngestionHumansIn patientTX341-641multiple food hypersensitivityIrritable bowel syndromeNutrition and Dieteticsbusiness.industryNutrition. Foods and food supplymedicine.diseaseWheat hypersensitivityHLACeliac Disease030104 developmental biologyDuodenal mucosa030211 gastroenterology & hepatologyneuropsychiatric symptomsFemalemedicine.symptomNervous System DiseasesbusinessClinical recordFood Science
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Anemia in Celiac Disease: Prevalence, Associated Clinical and Laboratory Features, and Persistence after Gluten-Free Diet

2022

Anemia is considered to be the most frequent extra-intestinal manifestation of Celiac Disease (CD). We assessed frequency, severity, morphologic features, and pathogenic factors of anemia in patients of the Sicilian Regional Network of Celiac Disease and attempted to identify putative pre-diet factors influencing anemia persistence. We retrospectively analyzed CD patients admitted to three centers between 2016–2020. 159 patients entered the study (129 females). More than half (54.7%) had mild-moderate, hypochromic and microcytic anemia, associated with below normal total serum iron and ferritin, indicative of iron deficiency anemia (IDA). One year after diagnosis, 134 patients were fo…

Celiac Disease; anemia; iron deficiency; gluten-free dietMedicine (miscellaneous)Celiac Disease anemia gluten-free diet iron deficiency
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Potential tolerability of ancient grains in non-celiac wheat sensitivity patients: A preliminary evaluation

2022

Background and aimsA wheat-free diet (WFD) represents the elective treatment for Non-celiac Wheat Sensitivity (NCWS) patients. Preliminary reports have shown a possible better tolerability of ancient grains in these subjects. The aim of this observational study was to evaluate the frequency of consumption of ancient grains and its correlation with clinical manifestations in NCWS patients.Methods223 NCWS patients were recruited, and their consumption of ancient grains was monitored. Participants were first administered a modified version of the Pavia/Biagi questionnaire to investigate their adherence to “modern WFD.” The appearance/exacerbation of symptoms after ingestion of ancient grains w…

Settore MED/09 - Medicina InternaGeneral MedicineAmylase-Trypsin Inhibitors (ATIs) Non-celiac Wheat Sensitivity (NCWS) ancient grains wheat free diet wheat tolerabilityFrontiers in Medicine
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