0000000000586989

AUTHOR

Antonio Falcó

0000-0001-6225-0935

showing 3 related works from this author

Transcriptomic and Genetic Associations between Alzheimer's Disease, Parkinson's Disease, and Cancer.

2021

Simple Summary Epidemiological studies have identified a link between neurodegenerative disorders and a reduced risk of overall cancer. Increases and decreases in the risk of site-specific cancers have also been reported. However, it is still unknown whether these associations arise due to shared genetic and molecular factors or are explained by other phenomena (e.g., biases in epidemiological studies or the use of medication). In this study, we aimed to investigate the potential molecular, genetic, and pharmacological links between Alzheimer’s and Parkinson’s diseases and a large panel of 22 cancer types. To examine the overlapping involvement of genes and pathways, we obtained differentia…

0301 basic medicineOncologyCancer ResearchParkinson's diseaseGenetic correlationsGenome-wide association studyDiseaseComorbidityParkinson Enfermedad de - Aspectos genéticos.chemistry.chemical_compound0302 clinical medicineExemestaneParkinson's disease - Genetic aspects.MedicineParkinsonCáncer - Aspectos genéticos.Càncer -- Aspectes genèticsRC254-282Alzheimer's disease - Genetic aspects.NeurodegenerationNeoplasms. Tumors. Oncology. Including cancer and carcinogensCódigo genético.comorbidityOncology:Informàtica::Aplicacions de la informàtica::Bioinformàtica [Àrees temàtiques de la UPC]medicine.medical_specialtyGenetic code.Alzheimer Enfermedad de - Aspectos genéticos.Article03 medical and health sciencesInternal medicineParkinson Malaltia dePI3K/AKT/mTOR pathwaygenetic correlationsCancer - Genetic aspects.business.industryCancertranscriptomicmedicine.diseaseComorbidityAlzheimer Malaltia d'030104 developmental biologychemistryTranscriptomicmeta-analysesMeta-analysesNeurodegenerative disordersAlzheimerGene expressionbusiness030217 neurology & neurosurgeryCancers
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A general framework for a class of non-linear approximations with applications to image restoration

2018

Este artículo se encuentra disponible en la página web de la revista en la siguiente URL: https://www.sciencedirect.com/science/article/abs/pii/S0377042717301188 Este es el pre-print del siguiente artículo: Candela, V., Falcó, A. & Romero, PD. (2018). A general framework for a class of non-linear approximations with applications to image restoration. Journal of Computational and Applied Mathematics, vol. 330 (mar.), pp. 982-994, que se ha publicado de forma definitiva en https://doi.org/10.1016/j.cam.2017.03.008 This is the pre-peer reviewed version of the following article: Candela, V., Falcó, A. & Romero, PD. (2018). A general framework for a class of non-linear approximations with applic…

Mathematical optimization010103 numerical & computational mathematics01 natural sciencesProjection (linear algebra)ConvexityImage (mathematics)symbols.namesakeProgramming (Mathematics) in Works of art.Convergence (routing)Applied mathematics0101 mathematicsProgramación (Matemáticas) - Aplicaciones en Obras de arte.Art - Conservation and restoration.Image restorationMathematicsApplied MathematicsHilbert space.Hilbert spaceAlgoritmos computacionales.Hilbert Espacio de.Linear subspaceComputer algorithms.010101 applied mathematicsComputational MathematicsObras de arte - Restauración.symbolsDeconvolutionObras de arte - Conservación.Journal of Computational and Applied Mathematics
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Antioxidant activity of 5-FU and new fluorinated uracil derivates

2017

The intake of antioxidants has increased in the last years in order to treat some pathologies associated with oxidative stress such as cancer, diabetes mellitus, atherosclerosis, myocardial infarction, acute pancreatitis, Parkinson's and Alzheimer's disease among others. In colorectal cancer, a widely antineoplastic drug used is the fluorinated uracil molecule 5-Fluorouracile (5-FU). The aim of this study is to assess the antioxidant capacity observed by the inhibition of lipid peroxidation by 5-FU and other fluorinated uracil derivates: 6-[Difluoro(phenyl)methyl]-3-(2,4,6-trifluorophenyl)pyrimidine-2,4(1H,3H)-dione (S-81), 3-[2-Chloroethyl]-6-[difluoro(phenyl)methyl]pyrimidine-2,4(1H,3H)-d…

AntioxidantPyrimidineChemistrymedicine.medical_treatmentTrolox equivalent antioxidant capacityCancerUracilPharmacologymedicine.disease_causemedicine.diseaseLipid peroxidationchemistry.chemical_compoundBiochemistryDiabetes mellitusmedicineOxidative stressProceedings of MOL2NET 2017, International Conference on Multidisciplinary Sciences, 3rd edition
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