0000000000589921

AUTHOR

Amparo Alegría-torán

showing 4 related works from this author

Bioavailability of minerals in foods

2015

Toxicological riskFood scienceBiologyBioavailability
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Changes inα-tocopherol and retinol levels during cardiopulmonary bypass correlate with maximal arterial partial pressure of oxygen

2007

Cardiopulmonary bypass (CPB) is associated with oxidative stress. This study examined antioxidant levels in adults undergoing CPB surgery and their correlation with clinical variables. Arterial blood samples were obtained from 27 patients undergoing CPB. The time-course variation of vitamin C (spectrofluorimetry), alpha-tocopherol and retinol (HPLC) levels were determined. Plasma vitamin C rose initially but gradually decayed during reperfusion until 60% reduction of baseline values post-surgery. alpha-Tocopherol and retinol were reduced along CPB with post-operative values approximately 25% lower than baseline. No significant changes were found for selenium and glutathione peroxidase. PaO(…

Malemedicine.medical_specialtyAntioxidantPartial Pressuremedicine.medical_treatmentalpha-TocopherolIschemiaAscorbic AcidBiochemistryAntioxidantslaw.inventionchemistry.chemical_compoundlawInternal medicinemedicineCardiopulmonary bypassHumansVitamin AChromatography High Pressure LiquidAgedchemistry.chemical_classificationCardiopulmonary BypassVitamin CChemistryGlutathione peroxidaseRetinolGeneral MedicineMiddle AgedHypothermiamedicine.diseaseSurgeryOxygenOxidative Stresssurgical procedures operativeEndocrinologyArterial bloodFemalemedicine.symptomcirculatory and respiratory physiologyFree Radical Research
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Bovine plasma hydrolysates' iron chelating capacity and its potentiating effect on ferritin synthesis in Caco-2 cells.

2020

The low bioavailability of iron is one factor that contributes to its deficiency in the human diet. For this reason, it is necessary to find compounds that can form iron chelates so that these can be added to foods that contain iron to improve its bioavailability at the intracellular level. In this study, we assessed the relationship between bovine plasma hydrolysates' iron chelating ability and their degree of hydrolysis. The hydrolysate with the highest chelating capacity was fractionated and each fraction's chelating capacity was subsequently assessed. Each fraction's effect on ferritin synthesis in Caco-2 cells was also determined. The results showed that bovine plasma hydrolysates with…

0301 basic medicineIronBiological AvailabilityIron Chelating AgentsHydrolysate03 medical and health sciencesHydrolysisPlasma0404 agricultural biotechnologyAnimalsHumansChelationSolubilityAmino AcidsChelating Agentschemistry.chemical_classification030109 nutrition & dieteticsbiologyChemistryHydrolysis04 agricultural and veterinary sciencesGeneral Medicine040401 food scienceBioavailabilityAmino acidDietFerritinBiochemistryCaco-2Ferritinsbiology.proteinCattleCaco-2 CellsFood ScienceFoodfunction
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Evaluation of the antioxidant capacity, furan compounds and cytoprotective/cytotoxic effects upon Caco-2 cells of commercial Colombian coffee.

2017

Abstract Antioxidant capacity (AC), total phenolics (TPs), furan compounds (HMF and furfural F) and cytoprotective/cytotoxic effects upon Caco-2 cells (MTT, cell cycle and reactive oxygen species (ROS)) were evaluated in Colombian coffee (2 ground and 4 soluble samples). The AC (ABTS and FRAP), TPs and HMF ranged between 124–722, 95–802 μmoles Trolox/g, 21–100 mg gallic acid/g and 69–2900 mg/kg, respectively. Pretreatment of cells for 24 h with lyophilized coffee infusions at the highest dose without cytotoxic effects (500 μg/mL) significantly prevented the decrease in cell viability compared to control stress with H2O2 (5 mM/2 h), recovering viability to values between 34% and 45% and rest…

AntioxidantCell Survivalmedicine.medical_treatmentmedicine.disease_causeCoffeeAntioxidantsAnalytical Chemistrychemistry.chemical_compound0404 agricultural biotechnologyPhenolsFuranmedicineHumansFood scienceGallic acidFuranschemistry.chemical_classificationReactive oxygen speciesABTSPlant Extracts04 agricultural and veterinary sciencesGeneral MedicineHydrogen Peroxide040401 food scienceOxidative StresschemistryBiochemistryTroloxCaco-2 CellsReactive Oxygen SpeciesOxidative stressIntracellularFood ScienceFood chemistry
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