0000000000590812

AUTHOR

Marc-andré Verner

showing 2 related works from this author

Early Life Exposure to Perfluoroalkyl Substances (PFAS) and ADHD: A Meta-Analysis of Nine European Population-Based Studies

2020

Introduction: To date, the evidence for an association between perfluoroalkyl substances (PFAS) exposure and attention deficit and hyperactivity disorder (ADHD) is inconclusive. Objective: We investigated the association between early life exposure to perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA), and ADHD in a collaborative study including nine European population-based studies, encompassing 4,826 mother-child pairs. Methods: Concentrations of PFOS and PFOA were measured in maternal serum/plasma during pregnancy, or in breast milk, with different timing of sample collection in each cohort. We used a validated pharmacokinetic model of pregnancy and lactation to estimate…

MaleHealth Toxicology and MutagenesisReproductive health and childbirth010501 environmental sciencesToxicology01 natural sciencesMedical and Health SciencesCohort Studies0302 clinical medicinePregnancyMedicine2.2 Factors relating to the physical environment030212 general & internal medicineAetiologyChildPediatricFluorocarbonsEarly life3. Good healthPeer reviewMilkBreast FeedingMental HealthAlkanesulfonic AcidsMeta-analysisChild PreschoolPrenatal Exposure Delayed EffectsEnvironmental PollutantsFemaleCaprylatesHumanPopulationMEDLINEMothers03 medical and health sciencesEnvironmental healthmental disordersHumansPreschool0105 earth and related environmental sciencesMilk Humanbusiness.industryResearchPublic Health Environmental and Occupational HealthEuropean populationEnvironmental Exposurebiochemical phenomena metabolism and nutritionAttention Deficit Hyperactivity Disorder (ADHD)Attention Deficit Disorder with HyperactivityAttention deficitbusinessEnvironmental SciencesEnvironmental Health Perspectives
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Evaluating the neurotoxic effects of lactational exposure to persistent organic pollutants (POPs) in Spanish children.

2012

Although the brain continues developing in the postnatal period, epidemiological studies on the effects of postnatal exposure to neurotoxic POPs through breast-feeding remain mostly inconclusive. Failure to detect associations between postnatal exposure and health outcomes may stem from the limitations of commonly employed approaches to assess lactational exposure. The aim of the present study was to assess whether lactational exposure to polychlorinated biphenyl-153 (PCB-153), dichlorodiphenyldichloroethylene (DDE), or hexachlorobenzene (HCB) as estimated with a physiologically based pharmacokinetic (PBPK) model, is associated with decrements in mental and psychomotor development scores of…

medicine.medical_specialtyDichlorodiphenyl DichloroethyleneBreastfeedingPhysiologyNeuropsychological TestsToxicologyBayley Scales of Infant DevelopmentModels BiologicalRisk AssessmentDevelopmental psychologychemistry.chemical_compoundChild DevelopmentCognitionPregnancyRisk FactorsEpidemiologymedicineHexachlorobenzeneHumansLactationPsychomotor learningPregnancyMilk Humanbusiness.industryGeneral NeuroscienceAge FactorsInfant NewbornBrainInfantHexachlorobenzenemedicine.diseasePolychlorinated BiphenylsBreast FeedingchemistryDichlorodiphenyldichloroethyleneMaternal ExposureSpainPrenatal Exposure Delayed EffectsLinear ModelsPopulation studyEnvironmental PollutantsFemaleNeurotoxicity SyndromesbusinessPsychomotor PerformanceNeurotoxicology
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