0000000000593839

AUTHOR

L. Marinaro

Valutazioni igienico-sanitarie delle acque in tre invasi artificiali della provincia di Palermo destinate al consumo umano

We report the physico-chemical and bacteriological characteristics of three Sicilian reservoirs. The aim of this study was the evaluation of the reservoirs' sanitary conditions, given tha the water is also used for human consumption. 114 samples (4 locations at each lake) were collected in the period from July 1995 to June 1996. We analysed temperature, pH, oxygen saturation, colour and parameters of water mineralization and pollution of natural or human origin.Pathogenic bacteria (Salòmonellae) and opportunistic patjogens such as Pseudomonas aeruginosa and Aeromonas spp. were also investigated. At present, results are not showing particular levels of pollution, and it seems there is no ris…

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Economic Consequences of Investing in Anti-HCV Antiviral Treatment from the Italian NHS Perspective: A Real-World-Based Analysis of PITER Data

OBJECTIVE:\ud We estimated the cost consequence of Italian National Health System (NHS) investment in direct-acting antiviral (DAA) therapy according to hepatitis C virus (HCV) treatment access policies in Italy.\ud \ud METHODS:\ud A multistate, 20-year time horizon Markov model of HCV liver disease progression was developed. Fibrosis stage, age and genotype distributions were derived from the Italian Platform for the Study of Viral Hepatitis Therapies (PITER) cohort. The treatment efficacy, disease progression probabilities and direct costs in each health state were obtained from the literature. The break-even point in time (BPT) was defined as the period of time required for the cumulativ…

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