0000000000594906

AUTHOR

Angellotti E.

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The cortisol burden in elderly subjects with metabolic syndrome and its association with low-grade inflammation

2019

Background: Elderly people are exposed to an increased load of stressful events and neuro-hormonal stimulation is a key finding in metabolic syndrome and its related disorders. Aims: To determine the role of cortisol in elderly subjects, with or without metabolic syndrome (MetS), by means of a national multicentre observational study, AGICO (AGIng and Cortisol). Methods: From 2012 to 2017, the AGICO study enrolled n.339 subjects (aged > 65), after obtaining their informed consent. The investigators assessed a cardio-metabolic panel (including electrocardiogram, carotid ultrasonography and echocardiography), the presence of MetS (on Adult Treatment Panel III criteria), a neurological exam…

MaleAgingmedicine.medical_specialtySettore MED/09 - Medicina InternaHydrocortisoneUrinary systemNeurological examinationUrineGastroenterologyCortisolaging; cortisol; Inflammation; metabolic syndrome; aged; aged; 80 and over; echocardiography; female; humans; hydrocortisone; inflammation; male; metabolic syndromeExcretionAging; Cortisol; Inflammation; Metabolic syndrome; Aged; Aged 80 and over; Echocardiography; Female; Humans; Hydrocortisone; Inflammation; Male; Metabolic Syndrome03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicine80 and overmedicineHumans030212 general & internal medicineAgedAged 80 and overInflammationCreatininemedicine.diagnostic_testbusiness.industryCarotid ultrasonographymedicine.diseaseMetabolic syndromechemistryEchocardiographyFemaleGeriatrics and GerontologyMetabolic syndromebusiness030217 neurology & neurosurgeryHormone
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