0000000000595044

AUTHOR

Mercè Llabrés

0000-0002-5358-6768

showing 3 related works from this author

MetNet: A two-level approach to reconstructing and comparing metabolic networks

2021

Metabolic pathway comparison and interaction between different species can detect important information for drug engineering and medical science. In the literature, proposals for reconstructing and comparing metabolic networks present two main problems: network reconstruction requires usually human intervention to integrate information from different sources and, in metabolic comparison, the size of the networks leads to a challenging computational problem. We propose to automatically reconstruct a metabolic network on the basis of KEGG database information. Our proposal relies on a two-level representation of the huge metabolic network: the first level is graph-based and depicts pathways a…

Computer scienceEnzyme MetabolismMetabolic networkcomputer.software_genreBiochemistryInfographics0302 clinical medicineCluster AnalysisEnzyme ChemistryData ManagementMammals0303 health sciencesMultidisciplinaryBasis (linear algebra)Settore INF/01 - InformaticaQRChemical ReactionsEukaryotaGraphChemistryVertebratesPhysical SciencesMedicineCarbohydrate MetabolismData miningMetabolic PathwaysComputational problemGraphsNetwork AnalysisMetabolic Networks and PathwaysResearch ArticleComputer and Information SciencesComputingMethodologies_SIMULATIONANDMODELINGScience03 medical and health sciencesMetabolic NetworksSimilarity (psychology)Xenobiotic MetabolismAnimalsHumansMetabolomicsKEGGRepresentation (mathematics)Symbiosis030304 developmental biologyData VisualizationOrganismsBiology and Life SciencesMetabolismMetabolic pathwayComputingMethodologies_PATTERNRECOGNITIONMetabolismAmniotesEnzymologycomputerZoology030217 neurology & neurosurgerySoftwarePLoS ONE
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An update on the Symbiotic Genomes Database (SymGenDB): a collection of metadata, genomic, genetic and protein sequences, orthologs and metabolic net…

2020

The Symbiotic Genomes Database (SymGenDB; http://symbiogenomesdb.uv.es/) is a public resource of manually curated associations between organisms involved in symbiotic relationships, maintaining a catalog of completely sequenced/finished bacterial genomes exclusively. It originally consisted of three modules where users could search for the bacteria involved in a specific symbiotic relationship, their genomes and their genes (including their orthologs). In this update, we present an additional module that includes a representation of the metabolic network of each organism included in the database, as Directed Acyclic Graphs (MetaDAGs). This module provides unique opportunities to explore the…

Metabolic networkGenomicsBacterial genome sizeBiologycomputer.software_genreGenomeGeneral Biochemistry Genetics and Molecular BiologyBacterial genetics03 medical and health sciences0302 clinical medicineDatabases GeneticSymbiosisGeneOrganism030304 developmental biologyMetadata0303 health sciencesDatabaseGenomicsMetadataDatabase UpdateGeneral Agricultural and Biological SciencescomputerGenome BacterialMetabolic Networks and Pathways030217 neurology & neurosurgeryInformation Systems
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The Metabolic Building Blocks of a Minimal Cell

2020

This article belongs to the Section Evolutionary Biology.

0301 basic medicineMinimal gene set machineryMetabolic networkBacterial genome sizeComputational biologyMetabolic networksBiologyGenomeGeneral Biochemistry Genetics and Molecular BiologyArticle03 medical and health sciences0302 clinical medicineminimal gene set machinerylcsh:QH301-705.5Nasuia deltocephalinicolaGeneral Immunology and Microbiologydirected acyclic graphsDirected acyclic graphDirected acyclic graphs030104 developmental biologylcsh:Biology (General)Essential geneminimal cellsMinimal cellsCore (graph theory)metabolic networksGraph (abstract data type)General Agricultural and Biological Sciences030217 neurology & neurosurgeryBiology
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