0000000000597197
AUTHOR
David Guiraud
Electrophysiological Effects of Direct Electrical Stimulations During Awake Brain Surgery: Methodological Considerations
International audience; IRECT electrical stimulation (DES) has long been used to perform real-time functional mapping of the brain. More recently, this technique was introduced in the neurosurgery of slow-growing and infiltrative brain tumors to guide the resection with great success. By generating transient perturbations, this method allows the real-time identification of both cortical areas and subcortical networks that are essential for the function. Thus, as much as possible, non-functional tissue can be removed while minimizing the sequelae. However, the understanding of the electrophysiological effects of DES and, in particular its remote propagation, remains an open and key question.…
Case report: Remote neuromodulation with direct electrical stimulation of the brain, as evidenced by intra-operative EEG recordings during wide-awake neurosurgery
Letter to the editor; International audience
Awake Surgery: Skills of Neurosurgeon Matter but Those of Patient Too. How to Optimize Functional Brain Mapping by Improving Per-Operatory Testing?
International audience; It is now possible to perform resections of slowgrowing tumors in awake patients. Using direct electrical stimulation (DES), real-time functional mapping of the brain can be used to prevent the resection of essential areas near the tumor. For now, simple clinical tests are performed on conscious patients and combined with DES in order to discriminate functional and non-functional areas invaded by the tumors. In this work we try to develop a simple device based on a simple technology to better quantify the performances of the patients during the surgery itself and give a real-time feedback to the neurosurgeon that will help to further guide the surgery by improving th…
"Awake Surgery" of Slow-Growing Tumors and Cortical Excitability Measured by EEG Recordings. Preliminary Results
International audience; To investigate interhemispheric imbalance following "awake surgeries" of slow-growing tumors we recorded EEG in a visuo-manual RT paradigm. Increase of cortical excitability within the ipsilesional hemisphere was signed by increased ERPs amplitude for two patients. The cortical excitability in the lesioned hemisphere may be increased to maintain performances and cerebral plasticity.