0000000000598795

AUTHOR

Paolo Falaschi

showing 4 related works from this author

Vertebral fractures, function and cognitive status in osteoporotic hip fractured women: The FOCUS study

2017

Introduction Osteoporosis is characterized by low bone mass and microarchitectural modifications of bone tissue, with a consequent increase in fragility fractures. Vertebral fractures (VF) are the most prevalent osteoporotic fractures and osteoporotic hip fractures are the most serious complication of osteoporosis. The objectives of the present study were to determine the prevalence of VF in osteoporotic hip fractured women and to evaluate their association with pre-existing factors such as activities of daily living, quality of walking, numbers of falls, cognitive aspects and comorbidities. Material and methods Twenty-five departments of Orthopaedics, Rehabilitation and Geriatrics particip…

medicine.medical_specialtyActivities of daily livingmedicine.medical_treatmentOsteoporosis030209 endocrinology & metabolismHip fracture03 medical and health sciences0302 clinical medicineSpinal fracturemedicine030212 general & internal medicineFamily historyGeriatricsSpinal fractureHip fractureRehabilitationbusiness.industryActivities of daily livingOsteoporosimedicine.diseaseCognitive impairmentOrthopedic surgeryPhysical therapyGeriatrics and GerontologybusinessGerontologyEuropean Geriatric Medicine
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Improving adherence in osteoporosis: a new management algorithm for the patient with osteoporosis

2011

Introduction: Bisphosphonates are the first-choice treatment for osteoporosis. They effectively increase bone mineral density, reduce markers of bone resorption, and lower the incidence of new fractures in patients with osteoporosis-related fracture. However, the efficacy observed in clinical trials may not be realized in a real-life setting, partly due to poor adherence to therapy, with a significant worsening of clinical outcomes. Several issues contribute to poor adherence to osteoporosis medication, including inconvenient dosing regimens and concerns about possible adverse events. Although strategies to improve adherence have been investigated, new approaches are required. Areas covered…

medicine.medical_specialtyBone Density Conservation AgentBone densityOsteoporosisAlternative medicineadherence; osteoporosis; treatment algorithm; bone density; medication possession ratio; bisphosphonatesMedication AdherenceClinical ProtocolsCost of IllnessTreatment algorithmmedicineHumansBisphosphonatePharmacology (medical)DosingClinical ProtocolAdverse effectMED/01 - STATISTICA MEDICAOsteoporosis PostmenopausalAdherence bisphosphonates bone density medication possession ratio osteoporosis treatment algorithmMedication possession ratioPharmacologyBone Density Conservation Agentsbusiness.industryOsteoporosiGeneral Medicinemedicine.diseaseAlgorithmCost of IllneClinical trialBone Density Conservation AgentsTreatment OutcomeZoledronic acidAdherenceAdherence; Bisphosphonates; Bone density; Medication possession ratio; Osteoporosis; Treatment algorithm; Algorithms; Bone Density Conservation Agents; Clinical Protocols; Cost of Illness; Female; Humans; Osteoporosis; Osteoporosis Postmenopausal; Treatment Outcome; Medication Adherence; Pharmacology; Pharmacology (medical)Physical therapyOsteoporosisFemaleBone densitybusinessAlgorithmsHumanmedicine.drugExpert Opinion on Pharmacotherapy
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FRI0299 Prevalence of Vertebral Fractures in Osteoporotic HIP Fractured Patients: The Focus Study

2015

Background Osteoporosis is a multifactorial systemic skeletal disease, characterized by low bone mass and microarchitectural modifications of bone tissue, with a consequent increase in fragility fractures [1]. Vertebral fractures are the most prevalent osteoporotic fractures and osteoporotic hip fractures are the most serious complication of osteoporosis resulting in increased mortality and high socio-economic cost [2,3]. The coexistence of these two pathological conditions in elderly patients has been previously described, leading to even worse functional outcomes than each one alone [4]. Objectives To determine the prevalence of vertebral fractures in osteoporotic hip fractured women and …

medicine.medical_specialtyHip fractureActivities of daily livingbusiness.industryImmunologyOsteoporosismedicine.diseaseGeneral Biochemistry Genetics and Molecular BiologyRheumatologyEpidemiologyPhysical therapyImmunology and AllergyMedicinemedia_common.cataloged_instanceEuropean unionComplicationbusinessConsensus developmentPathologicalmedia_commonAnnals of the Rheumatic Diseases
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Guidelines for the management of osteoporosis and fragility fractures

2018

The purpose of this document, a result of the harmonisation and revision of Guidelines published separately by the SIMFER, SIOMMMS/SIR, and SIOT associations, is to provide practical indications based on specific levels of evidence and various grades of recommendations, drawn from available literature, for the management of osteoporosis and for the diagnosis, prevention, and treatment of fragility fractures. These indications were discussed and formally approved by the delegates of the Italian Scientific Associations involved in the project (SIE, SIGG, SIMFER, SIMG, SIMI, SIOMMMS, SIR, and SIOT). The purpose of this document, a result of the harmonisation and revision of Guidelines publishe…

medicine.medical_specialtyBone densityOsteoporosis030204 cardiovascular system & hematologyEM - Original03 medical and health sciences0302 clinical medicineFragilityBone DensitymedicineSettore MED/33 - Malattie Apparato LocomotoreInternal MedicineHumans030212 general & internal medicineFractures; Osteoporosis; Therapy; Internal Medicine; Emergency Medicinebusiness.industryOsteoporosiEvidence-based medicinemedicine.diseaseFractures; Osteoporosis; TherapyFractureItalyFamily medicineEmergency MedicineOsteoporosisTherapybusinessFracturesOsteoporotic Fractures
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