0000000000598907

AUTHOR

Isaías Sanmartín

showing 2 related works from this author

Multicompartmental Lipopolyplex as Vehicle for Antigens and Genes Delivery in Vaccine Formulations

2021

Vector design and its characterization is an area of great interest in current vaccine research. In this article, we have formulated and characterized a multicompartmental lipopolyplex, which associates multiple liposomes and polyplexes in the same complex. These particles allow the simultaneous delivery of lipid or water-soluble antigens associated with genes to the same cell, in much higher amounts than conventional lipopolyplexes. The vector characterization and optimization were carried out using liposomes with entrapped carboxyfluorescein and adapted electrophoretic assays. Two types of lipopolyplexes (containing hydrophilic or lipophilic antigens) were employed to evaluate their inter…

liposomesFarmacologiaCelllcsh:RS1-441Pharmaceutical Science02 engineering and technology010402 general chemistry01 natural sciencesArticlelipopolyplexeslcsh:Pharmacy and materia medicaImmune systemAntigenvaccinemedicinemelanomaVacunacióVector (molecular biology)Melanomamulticompartmental lipopolyplexesLiposomebiologyChemistryMelanoma021001 nanoscience & nanotechnologymedicine.disease0104 chemical sciencesVaccinationmedicine.anatomical_structureBiochemistrynon-viral gene transferbiology.proteinantitumor immunizationAntibody0210 nano-technologyPharmaceutics
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Game-based learning supported by audience response tools: game proposals and preliminary assessment

2018

The so-called game-based learning strategies are based on introducing games in the classrooms to improve aspects such as student performance, concentration and effort. Currently, they provide a very useful resource to increase the motivation of university students, generating a better atmosphere among peers and between student and teacher, which in turn is generally translated into better academic results. However, the design of games that successfully achieve the desired teaching-learning objectives is not a trivial task. This work focuses on the design of games that allow the assessment of ICT-related university subjects. Specifically, three different games are proposed, all based on stud…

Game designHigher educationEducational systemsGame based learning010501 environmental sciences01 natural sciencesUndergraduate educationGame design0502 economics and businessMathematics educationComputingMilieux_COMPUTERSANDEDUCATIONLearningGame-based learning0105 earth and related environmental sciencesOnline platformsbusiness.industryTeaching05 social sciencesUndergraduate educationHigher EducationPsychologybusiness050203 business & managementAudience responseEducational systems
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