0000000000599890

AUTHOR

Chiara Molinari

showing 2 related works from this author

Eight-week consumption of milk enriched with omega 3 fatty acids raises their blood concentrations yet does not affect lipids and cardiovascular dise…

2014

Adequate concentrations of omega 3 fatty acids (FA) may be maintained by consuming foods naturally rich in or functional foods enriched with those essential FA. We assessed the effects of an 8-week consumption of milk enriched with 400. mg of omega 3 FA on blood lipid levels and selected cardiovascular risk factors in adult healthy volunteers. Participants (n= 157) were randomized to consume - for eight weeks - either 500. mL/day of 1% fat milk providing 150. mg of eicosapentaenoic (EPA), 150. mg of docosahexaenoic (DHA), and 100. mg of α-linolenic (ALA) acids or 500. mL/day of non-enriched 1% fat milk. At week 8, we observed significant increments of blood EPA and DHA in the intervention g…

PharmacologyEicosapentaenoic acidmedicine.diagnostic_testHomocysteineBlood lipidsPhysiologyMilk enriched with fish oilBiologyEicosapentaenoic acidLeukotriene B4Thromboxane B2Thromboxane B2chemistry.chemical_compoundDocosahexaenoic acidchemistryDocosahexaenoic acidHealthy volunteersmedicineDisease riskOmega 3 fatty acidPharmacology (medical)Food scienceLipid profileDocosahexaenoic acid; Eicosapentaenoic acid; Leukotriene B4; Milk enriched with fish oil; Omega 3 fatty acids; Thromboxane B2; Pharmacology; Pharmacology (medical); Food ScienceFood Science
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Quantitative fluorescence determination of long-fragment DNA in stool as a marker for the early detection of colorectal cancer

2008

Background: A variety of molecular markers have been evaluated for the development of a non-invasive approach to the diagnosis of colorectal cancer. We aimed to validate the diagnostic accuracy, using the same threshold as in the previous pilot study, of fluorescent long DNA test as a relatively simple and inexpensive tool for colorectal cancer detection.Methods: A case-control study was conducted on 100 healthy subjects and 100 patients at first diagnosis of colorectal cancer. Human long-fragment DNA in stool was quantified by fluorescence primers and a standard curve and expressed in DNA nanograms.Results: We validated the 25-ng value, which emerged as the most accurate cut-off in the pil…

MaleCancer ResearchdiagnosisAdenomatous Polyposis Coli Proteinlong-fragment DNAcolorectal cancercolorectal cancerlcsh:RC254-282Polymerase Chain ReactionPathology and Forensic MedicineFecesFluorescence long DNABiomarkers TumorHumanslcsh:QH573-671stoolEarly Detection of CancerAgedDNA PrimersFluorescent DyesAged 80 and overlcsh:CytologyCell BiologyGeneral MedicineDNAMiddle Agedlcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensCase-Control StudiesMolecular MedicineFemaleOtherTumor Suppressor Protein p53Colorectal Neoplasms
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