6533b826fe1ef96bd12848b4
RESEARCH PRODUCT
Eight-week consumption of milk enriched with omega 3 fatty acids raises their blood concentrations yet does not affect lipids and cardiovascular disease risk factors in adult healthy volunteers
Nicolò MauroMarina ScaviniEmanuele BosiCecilia PianiChiara MolinariClaudio GalliClaudia GuerraPatrizia Risésubject
PharmacologyEicosapentaenoic acidmedicine.diagnostic_testHomocysteineBlood lipidsPhysiologyMilk enriched with fish oilBiologyEicosapentaenoic acidLeukotriene B4Thromboxane B2Thromboxane B2chemistry.chemical_compoundDocosahexaenoic acidchemistryDocosahexaenoic acidHealthy volunteersmedicineDisease riskOmega 3 fatty acidPharmacology (medical)Food scienceLipid profileDocosahexaenoic acid; Eicosapentaenoic acid; Leukotriene B4; Milk enriched with fish oil; Omega 3 fatty acids; Thromboxane B2; Pharmacology; Pharmacology (medical); Food ScienceFood Sciencedescription
Adequate concentrations of omega 3 fatty acids (FA) may be maintained by consuming foods naturally rich in or functional foods enriched with those essential FA. We assessed the effects of an 8-week consumption of milk enriched with 400. mg of omega 3 FA on blood lipid levels and selected cardiovascular risk factors in adult healthy volunteers. Participants (n= 157) were randomized to consume - for eight weeks - either 500. mL/day of 1% fat milk providing 150. mg of eicosapentaenoic (EPA), 150. mg of docosahexaenoic (DHA), and 100. mg of α-linolenic (ALA) acids or 500. mL/day of non-enriched 1% fat milk. At week 8, we observed significant increments of blood EPA and DHA in the intervention group and a decrease in controls. No significant between-group differences at week 8 were observed in the lipid profile and other surrogate makers of cardiovascular disease, with the exception of homocysteine, whose levels remained stable in the intervention group, but increased in the control group (p<. 0.001). In conclusion, daily consumption of 500. mL of 1% fat milk enriched with omega-3 FA for eight weeks leads to higher blood levels of EPA and DHA, confirming that milk is an optimal matrix for the provision of important micronutrients.
year | journal | country | edition | language |
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2014-10-01 |