0000000000599915

AUTHOR

Vincenzo Poggi

showing 2 related works from this author

Road Traffic Pollution and Childhood Leukemia: A Nationwide Case-control Study in Italy

2016

Background The association of childhood leukemia with traffic pollution was considered in a number of studies from 1989 onwards, with results not entirely consistent and little information regarding subtypes. Aim of the study We used the data of the Italian SETIL case-control on childhood leukemia to explore the risk by leukemia subtypes associated to exposure to vehicular traffic. Methods We included in the analyses 648 cases of childhood leukemia (565 Acute lymphoblastic–ALL and 80 Acute non lymphoblastic-AnLL) and 980 controls. Information on traffic exposure was collected from questionnaire interviews and from the geocoding of house addresses, for all periods of life of the children. Re…

MyeloidMaleFuture studies010501 environmental sciencesSettore MED/42 - Igiene Generale E Applicata01 natural sciences0302 clinical medicineEconomicahemic and lymphatic diseasesMedicine030212 general & internal medicineChildRoad trafficacute non lymphoblastic leukemia; childhood; environment; leukemia; road traffic; air pollution; case-control studies; child; child preschool; female; humans; infant; Italy; leukemia myeloid acute; male; precursor cell lymphoblastic leukemia-lymphoma; risk; motor vehicles; medicine (all)LeukemiaTraffic pollutionMedicine (all)General MedicinePrecursor Cell Lymphoblastic Leukemia-LymphomaLeukemiaMotor VehiclesLeukemia Myeloid AcuteItalyAcute non Lymphoblastic LeukemiaSettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICARoad TrafficChild PreschoolFemaleMedical emergencyCase-Control StudieHumanRiskChildhood leukemiaSocio-culturaleAcuteEnvironmentPrecursor Cell Lymphoblastic Leukemia Lymphoma03 medical and health sciencesEnvironmental healthAir PollutionHumansPreschool0105 earth and related environmental sciencesbusiness.industryCase-control studyType specificAmbientaleInfantmedicine.diseaseChildhoodCase-Control StudiesMotor Vehiclebusiness
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A prospective, randomized study of empirical antifungal therapy for the treatment of chemotherapy-induced febrile neutropenia in children

2012

Given that the rationale for empirical antifungal therapy in neutropenic children is limited and based on adult patient data, we performed a prospective, randomized, controlled trial that evaluated 110 neutropenic children with persistent fever. Those at high risk for invasive fungal infections (IFI) received caspofungin (Arm C) or liposomal amphotericinB (Arm B); those with a lower risk were randomized to receive Arm B, C, or no antifungal treatment (Arm A). Complete response to empirical antifungal therapy was achieved in 90/104 patients (86·5%): 48/56 at high risk (85·7%) [88·0% in Arm B; 83·9% in Arm C (P = 0·72)], and 42/48 at low risk (87·5%) [87·5% in control Arm A, 80·0% Arm B, 94·1…

Malemedicine.medical_specialtyAntifungal AgentsNeutropeniaAntineoplastic AgentsOpportunistic InfectionsLower riskFever of Unknown Originlaw.inventionEchinocandinsLipopeptideschemistry.chemical_compoundRandomized controlled trialCaspofunginlawAmphotericin BInternal medicinemedicineHumansProspective StudiesChildProspective cohort studyempirical antifungal therapy children cancerbusiness.industryPatient SelectionInfantCancerHematologyLength of Staymedicine.diseaseConfidence intervalSurgeryHospitalizationTreatment OutcomeMycoseschemistryChild PreschoolFemaleCaspofunginbusinessEmpiric therapyFebrile neutropeniaBritish Journal of Haematology
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