0000000000601299

AUTHOR

Virgilio Clara

showing 5 related works from this author

Constipation severity is associated with productivity losses and healthcare utilization in patients with chronic constipation

2014

OBJECTIVE: We sought to evaluate the association between constipation severity, productivity losses and healthcare utilization in a national sample of Italian patients with chronic non-organic constipation (CC). METHODS: We enrolled 878 outpatients with CC. Clinical and demographic data were collected by physicians during clinical examinations. Patients completed a self-administered questionnaire (Patient Assessment of Constipation-Symptoms, PAC-SYM; Work Productivity and Activity Impairment; healthcare utilization, and Symptoms Checklist 90 Revised - Somatization Scale, SCL-90 R). RESULTS: Mean PAC-SYM score was 1.62 ± 0.69. Mean weekly sick time due to constipation was 2.7 ± 8.6 h and pro…

medicine.medical_specialtyConstipationChronic constipation; Cost-of-illness study; Direct cost; Functional constipation; Healthcare utilization; Indirect cost; Irritable bowel syndrome; Productivity loss; Oncology; Gastroenterologymacromolecular substancesIndirect costsdirect costMedicineIn patientIntensive care medicineProductivitycost-of-illness studyIrritable bowel syndromeirritable bowel syndromeChronic constipation; cost-of-illness study; direct cost; functional constipation; healthcare utilization; indirect cost; irritable bowel syndrome; productivity lossChronic constipationChronic constipationbusiness.industryGastroenterologyhealthcare utilizationfunctional constipationOriginal Articlesmedicine.diseaseproductivity lossOncologyHealthcare utilizationindirect costPhysical therapyFunctional constipationmedicine.symptombusinessUnited European Gastroenterology Journal
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Abincol® (Lactobacillus plantarum LP01, Lactobacillus lactis subspecies cremoris LLC02, Lactobacillus delbrueckii LDD01), an oral nutraceutical, prag…

2019

Chronic intestinal disorders (CID), including inflammatory bowel disease (IBD), such as ulcerative colitis and Crohn’s disease, irritable bowel syndrome (IBS), and diverticular disease (DD), are diseases that relapse episodes. There is evidence that patients with CID have intestinal dysbiosis, so probiotics may counterbalance the impaired microbiota. Therefore, the current survey evaluated the efficacy and safety of Abincol®,an oral nutraceuticalcontaining a probiotic mixture with Lactobacillus plantarum LP01 (1 billion of living cells), Lactobacillus lactis subspecies cremoris LLC02 (800 millions of living cells), and Lactobacillus delbrueckii LDD01 (200 millions of living cells), in 3,460…

Diverticular DiseasesMaleirritable bowel syndromeLactobacillus delbrueckiiProbioticsdiverticular diseaseAdministration OralInflammatory bowel disease irritable bowel syndrome diverticular disease probiotic surveyMiddle AgedInflammatory Bowel DiseasesLactobacillusinflammatory bowel diseaseChronic DiseaseDietary SupplementsHumansFemaleOriginal ArticlesurveySelf ReportprobioticLactobacillus plantarumActa bio-medica : Atenei Parmensis
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Bloating is associated with worse quality of life, treatment satisfaction, and treatment responsiveness among patients with constipation-predominant …

2016

Background The management of bloating is unclear and its relationship with patients' well-being and treatment satisfaction independent of other abdominal symptoms is uncharacterized. We evaluated the association of bloating with patient-reported outcomes. Methods Thirty-nine centers for functional gastrointestinal disorders joined the laxative inadequate relief survey. We enrolled 2203 consecutive outpatients with functional constipation (FC) or constipation-predominant irritable bowel syndrome (IBS-C) in two cross-sectional waves. Both wave 1 and 2 included the SF-12, the patient assessment of constipation-symptoms (PAC-SYM), and the treatment satisfaction questionnaire for medication (TSQ…

AdultMaleQuality of lifemedicine.medical_specialtyConstipationCross-sectional studyPhysiologyBloating; Chronic constipation; Functional constipation; Irritable bowel syndrome; Patient-reported outcomes; Quality of life; Treatment satisfaction; Physiology; Endocrine and Autonomic Systems; GastroenterologyBloating; Chronic constipation; Functional constipation; Irritable bowel syndrome; Patient-reported outcomes; Quality of life; Treatment satisfaction; Adult; Constipation; Cross-Sectional Studies; Female; Flatulence; Humans; Irritable Bowel Syndrome; Male; Middle Aged; Prevalence; Quality of Life; Surveys and QuestionnairesEndocrine and Autonomic System03 medical and health sciences0302 clinical medicineBloatingQuality of lifeSurveys and QuestionnairesInternal medicinePrevalencemedicineFlatulenceHumansIrritable bowel syndromePatient-reported outcomeChronic constipationSettore MED/12 - GastroenterologiaPatient-reported outcomesTreatment satisfactionBloating; Chronic constipation; Functional constipation; Irritable bowel syndrome; Patient-reported outcomes; Quality of life; Treatment satisfaction; Adult; Constipation; Cross-Sectional Studies; Female; Flatulence; Humans; Irritable Bowel Syndrome; Male; Middle Aged; Prevalence; Quality of Life; Surveys and Questionnaires; Physiology; Endocrine and Autonomic Systems; GastroenterologyEndocrine and Autonomic Systemsbusiness.industryChronic constipationBloatingSettore MED/09 - MEDICINA INTERNAGastroenterologyMiddle Agedmedicine.diseaseIrritable bowel syndromeSettore MED/18 - Chirurgia GeneraleCross-Sectional StudiesTolerability030220 oncology & carcinogenesisPhysical therapyFunctional constipationFemale030211 gastroenterology & hepatologymedicine.symptombusinessConstipationFunctional constipation
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Lactobacillus plantarum LP01, Lactobacillus lactis subspecies cremoris LLC02, and Lactobacillus delbrueckii LDD01) in patients undergoing bowel prepa…

2019

Bowel preparation (BP) for colonoscopy induces significantly changes in gut microbiota and elicit intestinal symptoms. Impaired microbiota causes an intestinal dysbiosis. Consequently, probiotics may counterbalance the disturbed microbiota after BP. The current survey evaluated the efficacy and safety of Abincol®,an oral nutraceuticalcontaining a probiotic mixture with Lactobacillus plantarum LP01 (1 billion of living cells), Lactobacillus lactis subspecies cremoris LLC02 (800 millions of living cells), and Lactobacillus delbrueckii LDD01 (200 millions of living cells), in 2,979 outpatients (1,579 males and 1,400 females, mean age 56 years) undergoing BP. Patients took 1 stick/daily for 4 w…

MaleLactobacillus delbrueckiigut microbiotaProbioticsColonoscopyMiddle AgedLactobacillusPreoperative Carebowel preparationDysbiosisHumansFemaleOriginal Articlesurveybowel preparation gut microbiota colonoscopy probiotics surveyLactobacillus plantarumActa bio-medica : Atenei Parmensis
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Post-surgical intestinal dysbiosis: use of an innovative mixture (Lactobacillus plantarum LP01, Lactobacillus lactis subspecies cremoris LLC02, Lacto…

2019

Abdominal surgery represents a high risk for hospital-acquired infections and complication that may compromise the surgery outcome. Patients with recent abdominal surgery have an intestinal dysbiosis. There is evidence that probiotics may counterbalance the impaired microbiota. Therefore, the current survey evaluated the efficacy and safety of Abincol®,an oral nutraceuticalcontaining a probiotic mixture with Lactobacillus plantarum LP01 (1 billion of living cells), Lactobacillus lactis subspecies cremoris LLC02 (800 millions of living cells), and Lactobacillus delbrueckii LDD01 (200 millions of living cells), in 612 outpatients (344 males and 268 females, mean age 58 years) undergoing diges…

MaleLactobacillus delbrueckiiProbioticsDigestive surgery dysbiosis microbiota probiotic surveydysbiosisMiddle AgedGastrointestinal MicrobiomeLactobacillusPostoperative ComplicationsTreatment OutcomeAbdomenmicrobiotaHumansdigestive surgeryFemaleOriginal ArticlesurveyprobioticLactobacillus plantarumActa bio-medica : Atenei Parmensis
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