Functional regulation of the Werner protein by poly(ADP-ribose) and PARP-1

Effects of Training-Induced Fatigue on Pacing Patterns in 40-km Cycling Time Trials

In some endurance sports, athletes complete several competitions within a short period, resulting in accumulated fatigue. It is unclear whether fatigued athletes choose the same pacing pattern (PP) as when they have recovered.This study aimed to analyze effects of fatigue on PP of cyclists during a 40-km time trial (TT).Twenty-three male cyclists (28.8 ± 7.6 yr) completed three 40-km TT on a cycle ergometer. TT were conducted before (TT1) and after (TT2) a 6-d training period. A third TT was carried out after 72 h of recovery (TT3). Training days consisted of two cycling sessions: mornings, 1 h at 95% of lactate threshold or 3 × 5 × 30 s all-out sprint; afternoons, 3 h at 80% individual ana…