0000000000605569
AUTHOR
E. Straub
IgE in patients with glomerulonephritis and minimal-change nephrotic syndrome
Serum levels of IgE were studied in 30 children with minimal-change nephrotic syndrome and 32 children with mesangioproliferative glomerulonephritis during different stages of the disease and treatment. In addition, tissue obtained by renal biopsy was investigated by immunofluorescence histology; no deposits of IgE could be found. The serum IgE levels, however, were increased, particularly in patients with minimal-change nephrotic syndrome. It is concluded that IgE does not play a pathogenic role in the development of the renal disease, but that increased IgE levels are an indication of a disturbance of the immune system.
Ergebnisse von harnableitenden Operationen bei Blasenekstrophie
Bei 48 Kindern mit Blasenekstrophie und Epispadie, die in den Jahren 1964–1981 behandelt wurden, wurde bei 38 Patienten die Ureterosigmoideostomie mit antirefluxiver ureterocolischer Anastomose nach Goodwin (Abb. 1) durchgefuhrt. Bei den Fruhkomplikationen, die bei 5 Kindern innerhalb der ersten 3 postoperativen Monate auftraten, waren 3 Falle von akuter Pyelonephritis, bei einem Patienten wurde durch eine Dunndarmadhasion und in einem weiteren Fall durch eine Urinextravasation die operative Reintervention erforderlich.
Effect of L-thyroxine on renal excretion of water and electrolytes in both normal and mercury-intoxicated rats.
The urine output and the change in excretion of electrolytes (sodium, potassium, calcium, chloride, inorganic phosphate) in rats following mercury-induced acute tubular lesions showed marked recovery during L-thyroxine therapy. The kidney mechanisms responsible for this effect are discussed, considering especially the observation that rats treated with L-thyroxine have a reduced urinary output, unlike other species, including man, which react with polyuria. The oliguric effect of thyroid hormone in rats is attributed to the greater length of the vasa recta and loops of Henle.