0000000000605577

AUTHOR

Arrigo Moglia

showing 5 related works from this author

Botulinum Toxin Is Effective in the Management of Neurogenic Dysphagia. Clinical-Electrophysiological Findings and Tips on Safety in Different Neurol…

2017

Background and Aims: Neurogenic dysphagia linked to failed relaxation of the upper esophageal sphincter (UES) can be treated by injecting botulinum toxin (BTX) into the cricopharyngeal (CP) muscle. We compared the effects of this treatment in different neurological disorders with dysphagia, to evaluate its efficacy over time including the response to a second injection. Materials and Methods: Sixty-seven patients with neurogenic dysphagia associated with incomplete or absent opening of the UES (24 with brainstem or hemispheric stroke, 21 with parkinsonian syndromes, 12 with multiple sclerosis, and 10 with spastic-dystonic syndromes secondary to post-traumatic encephalopathy) were treated wi…

Side effectEncephalopathyupper esophageal sphincter dysmotilityneurogenic dysphagia03 medical and health sciences0302 clinical medicineSwallowingmedicineIngestionPharmacology (medical)botulinum toxinOriginal ResearchPharmacologybusiness.industryelectrophysiological study of swallowingMultiple sclerosiscricopharyngeal musclemedicine.diseaseDysphagiaBotulinum toxinPneumoniaAnesthesia030211 gastroenterology & hepatologymedicine.symptombusiness030217 neurology & neurosurgerymedicine.drugFrontiers in Pharmacology
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Electrophysiological patterns of oropharyngeal swallowing in multiple sclerosis.

2012

Abstract Objective We performed an electrophysiological study of swallowing (EPSS) in multiple sclerosis (MS) to describe oropharyngeal swallowing abnormalities and to analyze their correlations with dysphagia and with overall neurological impairment. Methods Neurological examinations were quantified using the Kurtzke Functional Systems and the Expanded Disability Status Scale (EDSS). Dysphagia was evaluated using the Dysphagia in Multiple Sclerosis (DYMUS) questionnaire, while fiberoptic endoscopic evaluation of swallowing (FEES) was used to establish the degree of aspiration and penetration, graded using the penetration–aspiration scale (PAS). The EPSS measured the duration of suprahyoid/…

AdultMalemedicine.medical_specialtyMultiple SclerosisOropharynxElectromyographyBladder Sphincter DysfunctionDysphagia swallowing electromiography multiple sclerosisSwallowingPhysiology (medical)otorhinolaryngologic diseasesmedicineHumansAgedExpanded Disability Status Scalemedicine.diagnostic_testbusiness.industryElectromyographyMultiple sclerosisMiddle Agedmedicine.diseaseDysphagiaSensory SystemsPathophysiologySurgeryDeglutitionNeurologyAnesthesiaFemaleNeurology (clinical)medicine.symptomAbnormalitybusinessDeglutition DisordersClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Electrophysiological Investigations of Shape and Reproducibility of Oropharyngeal Swallowing: Interaction with Bolus Volume and Age

2015

Electrophysiological assessment provides valuable information on physiological and pathophysiological characteristics of human swallowing. Here, new electrophysiological measures for the evaluation of oropharyngeal swallowing were assessed: (1) the activation pattern of the submental/suprahyoid EMG activity (SHEMG); (2) the reproducibility of the oral and pharyngeal phases of swallowing, by calculating the similarity index (SI) of the SHEMG (SI-SHEMG) and of the laryngeal-pharyngeal mechanogram (SI-LPM) during repeated swallows; and (3) kinesiological measures related to the LPM. An electrophysiological-mechanical method for measuring the activation pattern of the SHEMG, the SI-SHEMG, and t…

AdultMalemedicine.medical_specialtyBolus volumeOropharynxElectromyographySpeech and HearingYoung AdultAgeSwallowingMedicineHumansYoung adultAgedAged 80 and overReproducibilitymedicine.diagnostic_testbusiness.industryElectromyographyOtorhinolaryngology2734 Pathology and Forensic MedicineGastroenterologyReproducibility of ResultsDysphagiaMiddle AgedSwallowingDysphagiaReproducibilityDeglutitionAge; Bolus volume; Dysphagia; Electromyography; Reproducibility; Swallowing; Otorhinolaryngology2734 Pathology and Forensic Medicine; Gastroenterology; 3616ElectrophysiologyOtorhinolaryngologyOtorhinolaryngologyAnesthesiaSettore MED/26 - NeurologiaFemaleBolus (digestion)medicine.symptomLaryngeal Muscles3616businessDeglutition Disorders
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Specific patterns of laryngeal electromyography during wakefulness are associated to sleep disordered breathing and nocturnal stridor in multiple sys…

2016

Abstract Background Nocturnal stridor and respiratory abnormalities are important features of multiple system atrophy (MSA) with relevance to patient survival, and they are detected and evaluated mainly through video-polysomnography (video-PSG). Diurnal laryngoscopy seems to yield abnormal findings only in the presence of significant vocal cord (VC) dysfunction. Aim To assess whether specific electrophysiological patterns of diurnal EMG of VC muscles may indicate nocturnal stridor or respiratory dysfunctions in MSA patients. Materials and methods Seventeen patients with probable MSA were examined. A full-night video-PSG to collect standard breathing parameters (apnea/hypopnea index, mean Hb…

MaleStridorPolysomnographyLaryngoscopySeverity of Illness Index03 medical and health sciences0302 clinical medicineAtrophySleep Apnea SyndromesmedicineHumansRespiratory systemWakefulness030223 otorhinolaryngologyAgedRespiratory Soundsmedicine.diagnostic_testbusiness.industryElectromyographyApneaEMG abnormalityMiddle AgedMultiple System Atrophymedicine.diseasenervous system diseasesrespiratory tract diseasesCircadian RhythmNeurologyAnesthesiaWakefulnessFemaleNeurology (clinical)Geriatrics and Gerontologymedicine.symptomLaryngeal MusclesbusinessHypopnea030217 neurology & neurosurgeryParkinsonismrelated disorders
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The importance of the reproducibility of oropharyngeal swallowing in amyotrophic lateral sclerosis. An electrophysiological study

2017

Abstract Objective To investigate electrophysiologically the reproducibility of oropharyngeal swallowing in patients with ALS. Methods We enrolled 26 ALS patients, both with and without clinical signs of dysphagia, and 30 age-matched controls. The reproducibility of the electrophysiological signals related to the oral phase (electromyographic activity of the submental/suprahyoid muscles) and the pharyngeal phase (laryngeal-pharyngeal mechanogram) of swallowing across repeated swallows was assessed. To do this we computed two similarity indexes (SI) by using previously described mathematical algorithms. Results The reproducibility of oropharyngeal swallowing was significantly reduced both in…

MaleNeurologyElectromyographyAudiology0302 clinical medicineAmyotrophic lateral sclerosisDeglutition Disorder030223 otorhinolaryngologySimilarity indexmedicine.diagnostic_testdigestive oral and skin physiologyDysphagiaMiddle AgedDysphagiaSensory Systemsmedicine.anatomical_structureNeurologyAnesthesiaSuprahyoid musclesFemalemedicine.symptomCase-Control StudieHumanAdultmedicine.medical_specialtyReproducibility of Result03 medical and health sciencesstomatognathic systemSwallowingALS; Deglutition; Dysphagia; Electrophysiological evaluation of swallowing; Motor neuron disease; Similarity index; Adult; Aged; Amyotrophic Lateral Sclerosis; Case-Control Studies; Deglutition Disorders; Electromyography; Female; Humans; Male; Middle Aged; Pharynx; Reproducibility of Results; Deglutition; Sensory Systems; Neurology; Neurology (clinical); Physiology (medical)Physiology (medical)otorhinolaryngologic diseasesmedicineHumansMotor neuron diseaseAgedbusiness.industryElectromyographyPharynxAmyotrophic Lateral SclerosisReproducibility of Resultsmedicine.diseaseElectrophysiological evaluation of swallowingDeglutitionCase-Control StudiesPharynxNeurology (clinical)ALSbusinessSensory SystemDeglutition Disorders030217 neurology & neurosurgeryOropharyngeal dysphagiaAmyotrophic Lateral Sclerosi
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