0000000000605798

AUTHOR

H. Stege

showing 2 related works from this author

A randomized, multinational, noninferiority, phase III trial to evaluate the safety and efficacy of BF-200 aminolaevulinic acid gel vs. methyl aminol…

2018

Background: Basal cell carcinoma (BCC) represents the most common nonmelanoma skin cancer worldwide, affecting mainly adult, fair-skinned individuals. The World Health Organization distinguishes aggressive and nonaggressive forms, of which prototypical variants of the latter are primary nodular and superficial BCC. Objective: To demonstrate noninferiority of BF-200 ALA (a nanoemulsion gel containing 5-aminolaevulinic acid) compared with MAL (a cream containing methyl aminolaevulinate) in the treatment of nonaggressive BCC with photodynamic therapy (PDT). Noninferiority of the primary efficacy variable (overall patient complete response 12 weeks after last PDT) would be declared if the mean …

Malemedicine.medical_specialtySkin Neoplasmsmedicine.medical_treatmentSkin CreamPhotodynamic therapyDermatologyAdministration Cutaneouslaw.invention030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineRandomized controlled trialMethyl aminolevulinatelawCarcinomaHumansMedicineBasal cell carcinomaAgedSkinPhotosensitizing Agentsbusiness.industryActinic keratosisAminolevulinic AcidMiddle Agedmedicine.diseaseDermatologyClinical trialTreatment OutcomePhotochemotherapyCarcinoma Basal Cell030220 oncology & carcinogenesisFemaleSkin cancerbusinessmedicine.drugBritish Journal of Dermatology
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Characterization of commercial synthetic resins by pyrolysis-gas chromatography/mass spectrometry: application to modern art and conservation.

2009

To characterize a set of synthetic resins, a methodology by pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS) has been developed. The studied reference materials were commercial versions of a wide range of synthetic resins. For each polymer, the pyrolytic and chromatographic conditions were optimized to adequately resolve the fragment mixture in a short time. The proposed analytical method does not require previous treatment of the sample, and due to its high sensitivity, only a small sample quantity in the microgram range can be used. The pyrolysis temperature was found to have little effect on the obtained pyrograms. The summarized data set for the individual polymer materials, es…

chemistry.chemical_classificationChromatographyChromatographySynthetic resinChemistrySpectrometryChromatographic analysisObjectes d'art--Conservació i restauracióPyrolysis-gasPolymerMass spectrometryAnalytical methodSpectrum analysisAnalytical ChemistryCharacterization (materials science)Anàlisi espectralchemistry.chemical_compoundPyrolysis–gas chromatography–mass spectrometryMonomerArt objects--Conservation and restorationPyrolytic carbonCromatografiaSynthetic resinsModern artPyrolysisAnalytical chemistry
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