0000000000608468

AUTHOR

Berit Granum

showing 3 related works from this author

Prenatal exposure to phenols and lung function, wheeze, and asthma in school-age children from 8 European birth cohorts

2019

Prenatal exposure to phenolic compounds, widely used in many consumer products, can alter lung development and increase the risk of respiratory disorders in the offspring. However, evidence is scarce and mostly focused on bisphenol-A (BPA), although there are other substitutes that could also interfere with the developing respiratory system. We aim to estimate the association between exposure to 5 phenols during pregnancy (BPA, BPAF, BPB, BPF, and BPS) and lung function, wheeze, and asthma in school-age children. We included 2685 mother-child pairs from 8 European birth cohorts. Phenols concentrations were determined in urinary maternal samples collected during pregnancy (1999-2010). Betwee…

SpirometryPregnancymedicine.diagnostic_testbusiness.industryOffspringPhysiologyOdds ratioLogistic regressionmedicine.disease03 medical and health sciencesFEV1/FVC ratio0302 clinical medicine030228 respiratory systemWheezemedicine030212 general & internal medicinemedicine.symptombusinessAsthmaPaediatric respiratory epidemiology
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Prenatal exposure to perfluoroalkyl substances, immune-related outcomes, and lung function in children from a Spanish birth cohort study.

2019

Background: Prenatal exposure to perfluoroalkyl substances (PFASs) has been associated with impaired immune and respiratory health during childhood but the evidence is inconsistent and limited for lung function. We studied the association between prenatal PFASs exposure and immune and respiratory health, including lung function, up to age 7 years in the Spanish INMA birth cohort study. Methods: We assessed four PFASs in maternal plasma samples collected during the 1st trimester of pregnancy (years: 2003-2008): perfluorohexane sulfonate (PFHxS), perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), and perfluorononanoate (PFNA). Mothers reported the occurrence (yes/no) of lower respir…

SpirometryAdultVital capacityLongitudinal studyRespiratory diseasesEczemaPhysiology010501 environmental sciences01 natural sciences03 medical and health scienceschemistry.chemical_compound0302 clinical medicinePregnancyMedicineHumans030212 general & internal medicineImmune responseChildMaternal-Fetal ExchangeRespiratory Tract Infections0105 earth and related environmental sciencesAsthmaRespiratory SoundsPregnancyFluorocarbonsRespiratory tract infectionsmedicine.diagnostic_testbusiness.industryPublic Health Environmental and Occupational HealthInfantPrenatal exposure delayed effectsmedicine.diseaseAsthmaRespiratory Function TestsPerfluorooctanePerfluoroalkyl substanceschemistryAlkanesulfonic AcidsMaternal ExposureSpainRelative riskChild PreschoolPrenatal Exposure Delayed EffectsEnvironmental PollutantsFemaleCaprylatesbusinessBirth cohortInternational journal of hygiene and environmental health
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Prenatal exposure to perfluoroalkyl substances and immune and respiratory outcomes

2018

Prenatal exposure to perfluoroalkyl substances (PFAS) may be associated with impaired immune and respiratory health during childhood but the evidence is scarce and inconsistent. We studied the association between prenatal PFAS exposure and immune and respiratory health up to age 7 years in the Spanish INMA birth cohort (n=1188). We assessed perfluorohexane sulfonate (PFHxS), perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), and perfluorononanoate (PFNA) in maternal plasma samples. Mothers reported the occurrence (yes/no) of chest infections, lower respiratory tract infections, wheezing, asthma, and eczema in the previous 12 months at 1.5 and 4 years of the child and at 7 years. A…

SpirometryVital capacitymedicine.diagnostic_testRespiratory tract infectionsbusiness.industryPhysiologymedicine.diseasePerfluorooctanechemistry.chemical_compoundFEV1/FVC ratiochemistryRelative riskWheezemedicinemedicine.symptombusinessAsthma
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