0000000000611168

AUTHOR

Dorothée G. Drucker

0000-0003-0854-4371

showing 3 related works from this author

The evolution and changing ecology of the African hominid oral microbiome

2021

Significance The microbiome plays key roles in human health, but little is known about its evolution. We investigate the evolutionary history of the African hominid oral microbiome by analyzing dental biofilms of humans and Neanderthals spanning the past 100,000 years and comparing them with those of chimpanzees, gorillas, and howler monkeys. We identify 10 core bacterial genera that have been maintained within the human lineage and play key biofilm structural roles. However, many remain understudied and unnamed. We find major taxonomic and functional differences between the oral microbiomes of Homo and chimpanzees but a high degree of similarity between Neanderthals and modern humans, incl…

Neanderthalbindinggut microbiomemicrobiomeprimatePrehistòriaNeanderthalEvolutionsbiologiPrimatesalivary amylasePhylogeny0303 health sciencesMultidisciplinaryEcologyGeographybiologyEcologyMicrobiotaHuman microbiomeancientHominidae402SH6_2Biological SciencesBiological Evolutiongenomes suggestHuman evolution[SDE]Environmental SciencesOral MicrobiomeR-packagePan troglodytesdental plaque[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and PrehistoryEcology (disciplines)Socio-culturaleMicrobiologysalivary alpha-amylase03 medical and health sciencesbiology.animalDental calculus; microbiome; Neanderthal; primate; salivary amylaseAnimalsHumansMicrobiomevisualization030304 developmental biologyMouthperiodontal-diseaseEvolutionary BiologyGorilla gorillaBacteria030306 microbiologydental calculusDNAMikrobiologiBiofilmsFOS: Biological sciencesAnthropologyAfricaUpper PaleolithicMetagenome
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Palaeogenomics of Upper Palaeolithic to Neolithic European hunter-gatherers

2023

Acknowledgements: The authors thank G. Marciani and O. Jöris for comments on archaeology; C. Jeong, M. Spyrou and K. Prüfer for comments on genetics; M. O’Reilly for graphical support for Fig. 5 and Extended Data Fig. 9; the entire IT and laboratory teams at the Department of Archaeogenetics of MPI-SHH for technical assistance; M. Meyer and S. Nagel for support with single-stranded library preparation; K. Post, P. van Es, J. Glimmerveen, M. Medendorp, M. Sier, S. Dikstra, M. Dikstra, R. van Eerden, D. Duineveld and A. Hoekman for providing access to human specimens from the North Sea (The Netherlands); M. D. Garralda and A. Estalrrich for providing access to human specimens from La Riera (S…

HistoryAncient dnaInteractionsCave/45/23AdmixtureSettore BIO/08 - Antropologia/631/208/457/631/181/276160 Other humanitiesContaminationHumansHuntingPalaeogenomicsPopulation-structureArchaeology ; Biological anthropology ; Evolutionary genetics ; Population geneticsHistory AncientHuman evolutionDiversityOccupationMultidisciplinary/45Genome HumanarticlePaleontologyLast glacial maximumHuman GeneticsGene PoolGenomics/631/181/19/2471PleistoceneEuropeGenomic transformationsArchaeology/631/181/2474AnthropologyHunter-gatherersGenome sequence
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The genomic history of Southern Europe

2018

Farming was first introduced to southeastern Europe in the mid-7th millennium BCE - brought by migrants from Anatolia who settled in the region before spreading throughout Europe. However, the dynamics of the interaction between the first farmers and the indigenous hunter-gatherers remain poorly understood because of the near absence of ancient DNA from the region. We report new genome-wide ancient DNA data from 204 individuals-65 Paleolithic and Mesolithic, 93 Neolithic, and 46 Copper, Bronze and Iron Age-who lived in southeastern Europe and surrounding regions between about 12,000 and 500 BCE. We document that the hunter-gatherer populations of southeastern Europe, the Baltic, and the Nor…

0301 basic medicineMaleHistorySteppe01 natural sciencesgenome wide ancient DNA0302 clinical medicinepopulation dynamicsComputingMilieux_MISCELLANEOUSHistory Ancient2. Zero hunger0303 health scienceseducation.field_of_studyMultidisciplinarygeography.geographical_feature_categoryFarmersGenomeAgricultureCline (biology)GenomicsGrasslandEuropeGeographyWestern europeEthnologyFemalesoutheastern EuropeHumanArchaeogenetics010506 paleontologyAsia[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and PrehistoryHuman MigrationPopulationPopulationSettore BIO/08 - AntropologiaIndigenousArticleAncient03 medical and health sciencesgenetic variation ; genomics ; prehistoric Europe ; prehistoric archeology ; bioarchaeologyBioarchaeologygenomicsGeneticsHumansHUMANISTIC SCIENCES. Archeology.FarmerDNA AncientSex DistributioneducationMesolithic030304 developmental biology0105 earth and related environmental sciencesHUMANISTIČKE ZNANOSTI. Arheologija.Extramuralbusiness.industryGenome HumanAmbientaleDNAArchaeologyPRIRODNE ZNANOSTI. Biologija. Genetika evolucija i filogenija.genome wide ancient DNA; southeastern Europe; population dynamics030104 developmental biologyAncient DNAGenetics PopulationAgriculturegenetic variationAgriculture; Asia; DNA Ancient; Europe; Farmers; Female; Genetics Population; Genome Human; Grassland; History Ancient; Human Migration; Humans; Male; Sex Distribution; GenomicsAncient DNA Genomics Southeastern Europe Genetic VariationbusinessNATURAL SCIENCES. Biology. Genetics Evolution and Phylogenetics.030217 neurology & neurosurgery
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