0000000000611599
AUTHOR
Mostafá Elmasnaouy
showing 6 related works from this author
Triazolopyridines 21.1 The stereochemistry of 1-[1,2,3]triazolo[1,5-a] pyridin-7-yl-4-(2H-[1,2,3]triazol-4-yl)-1,3-butadienes and triazolo ring openi…
2002
The synthesis and NMR study of the geometry of 1-[1,2,3]triazolo[1,5-a]pyridin-7-yl-4-(2H[1,2,3]triazol-4-yl)-1,3-butadienes 1a, 1b, 5 and of new 1-(6-substituted-2-pyridyl)-4-(2H[1,2,3]triazol-4-yl)-1,3-butadienes 8-10 is reported. The stereochemistry of all butadienes studied is 1E, 3E except for compound 5 that is the 1Z, 3Z stereoisomer of 1a.
A facile route to new potential helicating ligands
1998
Abstract The synthesis of new bitriazolopyridines, 6,6′-disubstituted-2,2′-bipyridines and 2-pyridyl-6-(2-pyridylcarbonyl)-2-pyridylmethanone potential helicating ligands from 3-(2-aryl)-[1,2,3]triazolo[1,5-a]pyridines is described.
Triazolopyridines. 18. Nucleophilic substitution reactions on triazolopyridines; a new route to 2,2′-bipyridines
1997
Abstract The synthesis of some 5-, 6-, and 7-halogenotriazolopyridines is described, and their reactions with nucleophiles. The formation of 7,7′-bitriazolopyridines provides a new synthesis of 2,2′-bipyridines.
Evaluation and synthesis of 7-arylhydroxymethyltriazolopyridines as potential cardiovascular agents
2002
7-Arylhydroxymethyltriazolopyridines 3a-c and 4a-d were synthesized by regioselective lithiation of [1,2,3]triazolo[1,5-a]pyridines 1 and 2 and subsequent trapping of the 7-lithioderivatives formed using aryl aldehydes as electrophiles. The structural relationship between compounds 3a-c and 4a-d and arylethanolamines suggested their consideration as potential cardiovascular agents. A preliminary evaluation as vascular smooth muscle relaxants was carried out. These compounds did not act as α1-adrenoceptor antagonists and were unable to block calcium entry through voltage-dependent calcium channels. Abarca Gonzalez, Belen, Belen.Abarca@uv.es ; Ballesteros Campos, Rafael, Rafael.Ballesteros@uv…
ChemInform Abstract: A Facile Route to New Potential Helicating Ligands.
2010
Abstract The synthesis of new bitriazolopyridines, 6,6′-disubstituted-2,2′-bipyridines and 2-pyridyl-6-(2-pyridylcarbonyl)-2-pyridylmethanone potential helicating ligands from 3-(2-aryl)-[1,2,3]triazolo[1,5-a]pyridines is described.
Triazolopyridines 21.1 The stereochemistry of 1-[1,2,3]triazolo [1,5-a] pyridin-7-yl-4-(2h-[1,2,3]triazol-4-yl)-1,3-butadienes and triazolo ring open…
2002
The synthesis and NMR study of the geometry of 1-[1,2,3]triazolo[1,5-a]pyridin-7-yl-4-(2H- [1,2,3]triazol-4-yl)-1,3-butadienes 1a, 1b, 5 and of new 1-(6-substituted-2-pyridyl)-4-(2H- [1,2,3]triazol-4-yl)-1,3-butadienes 8-10 is reported. The stereochemistry of all butadienes studied is 1E, 3E except for compound 5 that is the 1Z, 3Z stereoisomer of 1a. Abarca Gonzalez, Belen, Belen.Abarca@uv.es ; Ballesteros Campos, Rafael, Rafael.Ballesteros@uv.es