Author: Rūta Melbārde

0000000000612402

AUTHOR

Rūta Melbārde

showing 2 related works from this author

Invazīvo gram negatīvo baktēriju jutība pret antibakteriālajiem līdzekļiem

2013

Darba mērķis bija analizēt un apkopot datus par gram negatīvo baktēriju rezistences izmaiņām Latvijas daudzprofilu klīnikā. Darbā tika aprakstīti biežāk izdalītie Enterobacteriaceae dzimtas pārstāvji, kā arī antibakteriālie līdzekļi un biežākie rezistences mehānismi pret tiem. Pētījuma dati, tika apkopoti no iepriekš divu gadu laikā veiktā darba bakterioloģijas laboratorijā. 2012.g. ir izdalīti vairāk mikroorganismi nekā 2011.g. Abos gados 3% no izdalītajiem celmiem ir rezistenti arī pret karbapenēmiem. 2012.g. 72% no celmiem ir rezistenti pret ampicilīnu. Rezumējot datus, nevar viennozīmīgi teikt, ka pieaug celmu skaits, kas ir rezistenti pret visiem antibakteriālajiem līdzekļiem, tomēr lī…

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EUCAST un CLSI metožu salīdzinājums paplašināta spektra βeta-laktamāžu noteikšanai Enterobacteriaceae dzimtas klīniskajos izolātos

2015

Darba mērķis bija salīdzināt EUCAST un CLSI antimikrobās jutības noteikšanas metodes paplašināta spektra β-laktamāžu noteikšanai Enterobacteriaceae dzimtas klīniskajos izolātos. Darba teorētiskajā daļā tika apskatīti biežākie ESBL producējošie Enterobacteriaceae dzimtas pārstāvji, antibakteriālo līdzekļu un rezistences mehānismu raksturojums. Dati iegūti 2014.-2015. g., strādājot klīniskajā mikrobioloģijas laboratorijā. Identificēti un pētīti 269 baktēriju izolāti. Pēc EUCAST standarta 55 izolātiem mainījās antibiogrammas rezultāti. Ceftazidīmam un cefotaksīmam samazinot antibakteriālā līdzekļa koncentrāciju pēc EUCAST standarta, tie tiek padarīti jutīgāki pret ESBL noteikšanu. Pateicoties …

ESBLEnterobacteriaceaeCLSIEUCASTBioloģija

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PEPhysical Sciences and Engineering
- PE2Fundamental Constituents of Matter
  - PE2_1Theory of fundamental interactions
  - PE2_2 Phenomenology of fundamental interactions
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  - PE2_7Nuclear and particle astrophysics
  - PE2_9 Electromagnetism
  - PE2_10Atomic, molecular physics
  - PE2_11Ultra-cold atoms and molecules
  - PE2_18Equilibrium and non-equilibrium statistical mechanics: steady states and dynamics
  - PE2_14Lasers, ultra-short lasers and laser physics
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  - PE2_16Non-linear physics
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  - PE2_13Quantum optics and quantum information
  - PE2_15Thermodynamics
- PE1Mathematics
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  - PE1_6Geometry and global analysis
  - PE1_8Analysis
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  - PE1_10ODE and dynamical systems
  - PE1_12Mathematical physics
  - PE1_11Theoretical aspects of partial differential equations
  - PE1_13Probability
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  - PE1_4 Algebraic and complex geometry
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- PE3Condensed Matter Physics
  - PE3_1Structure of solids, material growth and characterisation
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  - PE10_18Cryosphere, dynamics of snow and ice cover, sea ice, permafrosts and ice sheets
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- PE11Materials Engineering
  - PE11_2Engineering of metals and alloys
  - PE11_1Engineering of biomaterials, biomimetic, bioinspired and bio-enabled materials
  - PE11_3Engineering of ceramics and glasses
  - PE11_4Engineering of polymers and plastics
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  - PE11_8Engineering of alternative established or emergent materials
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  - PE11_12Semi-conducting and magnetic materials engineering
  - PE11_13Metamaterials engineering
  - PE11_14Computational methods for materials engineering
LSLife Sciences
- LS1Molecules of Life: Biological Mechanisms, Structures and Functions
  - LS1_2Biochemistry
  - LS1_1Macromolecular complexes including interactions involving nucleic acids, proteins, lipids and carbohydrates
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  - LS1_14Innovative methods and modelling in molecular, structural and synthetic biology
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- LS2Integrative Biology: from Genes and Genomes to Systems
  - LS2_1Genetics
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  - LS2_2Gene editing
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  - LS2_14Genetic diseases
  - LS2_16Innovative methods and modelling in integrative biology
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- LS4Physiology in Health, Disease and Ageing
  - LS4_1Organ and tissue physiology and pathophysiology
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  - LS4_3Physiology of ageing
  - LS4_2Comparative physiology
  - LS4_5Non-hormonal mechanisms of inter-organ and tissue communication
  - LS4_6Microbiome and host physiology
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- LS3Cell Biology, Development, Stem Cells and Regeneration
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  - LS3_8Embryogenesis, pattern formation, morphogenesis
  - LS3_9Cell differentiation, formation of tissues and organs
  - LS3_10Developmental genetics
  - LS3_11Evolution of developmental strategies
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  - LS3_3Cell behaviour, including control of cell shape, cell migration
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  - LS3_17Theoretical modelling in cellular, developmental and regenerative biology
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  - LS3_1Cell cycle, cell division and growth
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SHSocial Sciences and Humanities
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  - SH7_2Migration
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