Remineralization effects of conventional and experimental ion-releasing materials in chemically or bacterially-induced dentin caries lesions

Abstract Objectives The aim of this study was to evaluate the remineralization effects of conventional and experimental ion-releasing materials on different artificial dentin carious lesions. Methods Forty human dentin discs were submitted to different demineralization protocols for simulated caries lesion: (D1) Shallow chemically-induced caries, (D2) deep chemically-induced caries, (D3) deep bacterially-induced caries. Each disc was divided in five parts; one of those served as baseline control. The remaining parts of each disc (n = 12–16/group) were treated using the following materials: EXP, an experimental resin-based bioactive material consisting of a self-etch primer and an adhesive c…