0000000000616733

AUTHOR

Triolo Giovanni

showing 3 related works from this author

Vgamma9/Vdelta2 T lymphocytes in Italian patients with Behçet's disease: evidence for expansion, and tumour necrosis factor receptor II and interleuk…

2002

Behçet's disease is a multisystem disease in which there is evidence of immunological dysregulation. It has been proposed that gamma/delta T cells are involved in its pathogenesis. The aim of the present study was to assess the capacity of gamma/delta T cells with phenotype Vgamma9/Vdelta2, from a group of Italian patients with Behçet's disease, to proliferate in the presence of various phosphoantigens and to express tumour necrosis factor (TNF) and IL-12 receptors. Twenty-five patients and 45 healthy individuals were studied. Vgamma9/Vdelta2 T cells were analyzed by fluorescence activated cell sorting, utilizing specific monoclonal antibodies. For the expansion of Vgamma9/Vdelta2 T cells, …

AdultMaleBehçet's diseaseBehcet SyndromeT-LymphocytesReceptors Interleukin-12Receptors Antigen T-Cell gamma-deltaReceptors InterleukinMiddle AgedLymphocyte Activationγ/δ T lymphocyteReceptors Tumor Necrosis FactorPhenotypetumour necrosis factorItalyHumansFemaleinterleukin 12Cell DivisionCells CulturedResearch ArticleArthritis researchtherapy
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PLA1/A2 polymorphism of the platelet glycoprotein receptors IIIA in Behçet's disease

2010

OBJECTIVES: To investigate potential associations between the PlA1/A2 polymorphism of the platelet glycoprotein receptor IIIA (GpIIIa) gene and venous thrombosis and other clinical manifestations in Italian patients with Behçet's disease (BD). METHODS: Two hundred consecutive Italian patients satisfying the International Study Group criteria for BD who were followed up for seven years and 241 healthy Italian age- and gender-matched blood donors were molecularly genotyped for the PlA1/A2 polymorphism of the platelet GpIIIa gene; 118 and 117 of the 200 BD patients were also respectively genotyped for factor V Leiden and prothrombin gene G20210A polymorphisms. A standard microlymphocytotoxicit…

AdultBlood PlateletsMaleVenous ThrombosisPolymorphism GeneticAdolescentGenotypeBehcet SyndromeIntegrin beta3Factor VPLA1/2 polymorphism Behcet's diseaseYoung AdultHuman PlateletGene FrequencyGeneticHumansAntigens Human PlateletFemaleProthrombinAdolescent; Adult; Antigens Human Platelet; Blood Platelets; Factor V; Female; Gene Frequency; Genotype; Humans; Integrin beta3; Male; Polymorphism Genetic; Prothrombin; Young Adult; Behcet Syndrome; Venous ThrombosisAntigensPolymorphism
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Physical capacity in performing daily activities is reduced in scleroderma patients with early lung involvement

2014

BACKGROUND: Patients with systemic sclerosis (SSc) often complain reduced capacity at submaximal exercise; conversely physical capacity in performing daily duties has never been measured in SSc. OBJECTIVES: To evaluate this performance and its correlates, in patients with SSc compared to healthy controls, in a free-living setting. METHODS: Twenty-seven outpatients with stable SSc and 11 controls were recruited. Physical activity was assessed by portable multiple sensor device (SenseWear Armband) worn for at least six days. Physical activity duration (PAD; in minutes) for non-sedentary activities and physical activity level (PAL= total daily energy/resting energy expenditure) per day were ca…

AdultMaleScleroderma SystemicPhysical activityHypertension PulmonaryMiddle AgedSettore MED/10 - Malattie Dell'Apparato RespiratorioLung functionSclerodermaNutrition AssessmentSpirometryActivities of Daily LivingHumansMotion sensorFemaleExerciseAged
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