0000000000616947
AUTHOR
Carlos Clavel
Tratamiento profiláctico por anaerobios con oxígeno hiperbárico
The authors report their experience in the use of hyperbaric camera in the management of anaerobic infections after important traumatisms throughout the period of time 1984-1985. A double blind study is carried out. The first group includes those patients under treatment with hyperbaric oxygen, once the anaerobic infection has been detected. The second group is formed by patients who received, during the 24 hours after the accident, profilactic treatment in the hyperbaric camera. The results obtained in the first group were 84'3% good, whilst in the second group there were no cases of anaerobic infection. Therefore, these results Jed authors believe that the use of hyperbaric oxygen must be…
In vitro and in vivo arterial differentiation of human multipotent adult progenitor cells
Many stem cell types have been shown to differentiate into endothelial cells (ECs); however, their specification to arterial or venous endothelium remains unexplored. We tested whether a specific arterial or venous EC fate could be induced in human multipotent adult progenitor cells (hMAPCs) and AC133(+) cells (hAC133(+)). In vitro, in the presence of VEGF(165), hAC133(+) cells only adopted a venous and microvascular EC phenotype, while hMAPCs differentiated into both arterial and venous ECs, possibly because hMAPCs expressed significantly more sonic hedgehog (Shh) and its receptors as well as Notch 1 and 3 receptors and some of their ligands. Accordingly, blocking either of those pathways …