Multiple HAT transporters regulate dopaminergic transmission and sleep in Drosophila

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Get more details on amino acid transporters changing Drosophila's mind.... 17. rencontre du Club de neurobiologie des invertébrés

Rôle du transporteur d'acides aminés Minidiscs dans le fonctionnement du système nerveux chez Drosophila melanogaster

Amino acids have many functions in the body in addition to their role as basic constituents of proteins. They can for example serve as a neurotransmitter or signal for the activation of intracellular pathways. Carriers of the SLC protein family facilitate their path through the plasma membrane. The heterodimeric amino acid transporters HAT belong to SLC proteins. HAT are composed of a light chain SLC7 ensuring the specificity of transport and a heavy chain SLC3 involved in the addressing of the protein complex to the plasma membrane. My thesis focused on studying the role of a SLC7 homologue in drosophila, Minidiscs (Mnd), in the functioning of the nervous system. Mnd might belong to system…