Author: Andrea Wangorsch

0000000000621328

AUTHOR

Andrea Wangorsch

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Component-Resolved Diagnosis of American Cockroach (Periplaneta americana) Allergy in Patients From Different Geographical Areas

2021

Background:Manifestation of respiratory allergy to American cockroach (Periplaneta americana) is prominent in the subtropical and tropical areas. However, co-existing perennial indoor inhalant allergies frequently compromise clinical diagnosis of cockroach allergy, and the analysis of sensitization pattern is limited by the lack ofPeriplanetaallergens widely available for component-resolved diagnostics (CRD).Objective:To evaluate a collection of previously described recombinantPeriplanetaallergens for CRD in cockroach allergy.Methods:A panel of nine recombinantPeriplaneta allergens (Per a 1–5, 7–10) was generated, purified, and subjected to physicochemical characterization by applying circu…

0301 basic medicinecomponent-resolved diagnosisAllergyanimal structuresPeriplaneta americana (Insecta)medicine.disease_causeAmerican cockroachMicrobiology03 medical and health sciences0302 clinical medicineAllergenimmune system diseasesbiology.animalmedicineIn patientSensitizationCockroachbiologyGeneral MedicineRC581-607biology.organism_classificationmedicine.diseaserespiratory tract diseasesBlattella germanica030104 developmental biologymedicine.anatomical_structure030228 respiratory systemCockroach allergycockroach allergyImmunologic diseases. AllergyAmerican cockroachAmerican cockroach ; Blattella germanica ; component-resolved diagnosis ; cockroach allergy ; Periplaneta americana (Insecta) ; InsektenallergiePeriplanetaFrontiers in Allergy

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