0000000000625856

AUTHOR

Alessandra Ravaioli

0000-0002-8778-6397

showing 5 related works from this author

Survival and cure trends for European children, adolescents and young adults diagnosed with acute lymphoblastic leukemia from 1982 to 2002

2013

Proportion cured is a potentially more informative cancer outcome measurement than 5-year survival. We present population-based estimates of cure for young patients diagnosed with acute lymphoblastic leukemia in Europe from 1982 to 2002. Thirty-five European cancer registries provided data. Survival was estimated by age, period of diagnosis and European region, and used as input for parametric cure models, which assume cured patients have the same mortality as the general population. For acute lymphoblastic leukemia diagnosed in 1–14 year olds in 2000–2002, over 77% were estimated cured. The proportion cured improved significantly over the study period: an impressive 26–58% in infants (up t…

MalePediatricsmedicine.medical_specialtyAdolescentLymphoblastic LeukemiaPopulationacute lymphoblastic leukemiaHistory 21st Centuryacute lymphoblastic leukemia; children; adolescents and young adults; survival and cure trendsEurope/epidemiologyYoung AdultchildrenHumansMedicineRegistriesYoung adultChildeducationddc:613education.field_of_studybusiness.industryAge FactorsInfant NewbornAbsolute risk reductionInfantCancerHematologyPrecursor Cell Lymphoblastic Leukemia-LymphomaHistory 20th CenturyEuropean regionmedicine.diseasesurvival and cure trendsPrecursor Cell Lymphoblastic Leukemia-Lymphoma/epidemiology/history/mortalityChild PreschoolEarly adolescentsFemaleOriginal Articles and Brief Reportsbusinessadolescents and young adultsHaematologica
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The impact of overdiagnosis on thyroid cancer epidemic in Italy,1998-2012

2018

Aims: In Italy, incidence rates of thyroid cancer (TC) are among the highest world- wide with substantial intracountry heterogeneity. The aim of the study was to examine time trends of TC incidence in Italy and to estimate the proportion of TC cases potentially attribut- able to overdiagnosis. Methods: Data on TC cases reported to Italian cancer registries during 1998e2012 aged <85 years were included. Age-standardised incidence rates (ASR) were computed by sex, period, and histology. TC overdiagnosis was estimated by sex, period, age, and Italian region. Results: In Italy between 1998e2002 and 2008e2012, TC ASR increased of 74% in women (from 16.2 to 28.2/100,000) and of 90% in men (fro…

MaleCancer ResearchMedical OveruseSettore MED/42 - Igiene Generale E Applicata0302 clinical medicineRegistriesYoung adultOverdiagnosisChildThyroid cancerAged 80 and overeducation.field_of_studyIncidence (epidemiology)IncidenceThyroidTime trendsMiddle Agedmedicine.anatomical_structureOncologyItaly030220 oncology & carcinogenesisChild PreschoolFemalemedicine.symptomAdultIncidence; Italy; Mortality; Overdiagnosis; Thyroid cancer; Time trends; Oncology; Cancer ResearchOverdiagnosisAdolescentPopulationSocio-culturale030209 endocrinology & metabolismAsymptomaticThyroid cancer03 medical and health sciencesYoung AdultmedicineHumansThyroid NeoplasmsMortalityeducationEpidemicsAgedbusiness.industryInfant NewbornCancerInfantmedicine.diseaseOverdiagnosibusinessDemography
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Trends in Net Survival from Vulvar Squamous Cell Carcinoma in Italy (1990–2015)

2023

(1) Objective: In many Western countries, survival from vulvar squamous cell carcinoma (VSCC) has been stagnating for decades or has increased insufficiently from a clinical perspective. In Italy, previous studies on cancer survival have not taken vulvar cancer into consideration or have pooled patients with vulvar and vaginal cancer. To bridge this knowledge gap, we report the trend in survival from vulvar cancer between 1990 and 2015. (2) Methods: Thirty-eight local cancer registries covering 49% of the national female population contributed the records of 6274 patients. Study endpoints included 1- and 2-year net survival (NS) calculated using the Pohar-Perme estimator and 5-year NS condi…

trendvulvar neoplasmvulvar neoplasmsGeneral MedicineSettore MED/42 - Igiene Generale E Applicatavulvar neoplasms; survival; trendsurvivalJournal of Clinical Medicine
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Incidence trends of vulvar squamous cell carcinoma in Italy from 1990 to 2015

2020

The incidence of vulvar squamous cell carcinoma has increased for decades in most Western countries - a trend virtually restricted to women aged50 or 60 years. In southern Europe, conversely, the trends have been insufficiently studied. This article reports a study from Italy.Thirty-eight local cancer registries, currently covering 15,274,070 women, equivalent to 49.2% of the Italian national female population, participated. Invasive cancers registered between 1990 and 2015 with an International Classification of Diseases for Oncology, 3rd revision, topography code C51 and morphology codes compatible with vulvar squamous cell carcinoma (n = 6294) were eligible. Incidence trends were analyse…

0301 basic medicineHistoryVulvar Squamous Cell CarcinomaAge-period-cohort modelling; Incidence; Trend; Vulvar neoplasms; Carcinoma Squamous Cell; Female; History 20th Century; History 21st Century; Humans; Incidence; Italy; Middle Aged; Vulvar NeoplasmsSettore MED/42 - Igiene Generale E ApplicataHistory 21st CenturyNO03 medical and health sciences0302 clinical medicineAge-period-cohort modellingAge-period-cohort modelling; Incidence; Trend; Vulvar neoplasmsTrendHumansMedicineRisk factorVulvar neoplasmVulvar Neoplasmsbusiness.industryIncidenceIncidence (epidemiology)CarcinomaObstetrics and GynecologyHistory 20th CenturyMiddle Aged21st CenturyConfidence intervalCancer registry20th CenturyTrend analysis030104 developmental biologySquamous CellItalyOncology030220 oncology & carcinogenesisVulvar neoplasms incidence trend age-period-cohort modellingCarcinoma Squamous CellFemalebusinessDemographyCohort studyGynecologic Oncology
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Italian cancer figures, report 2013: Multiple tumours

2013

This collaborative study, based on data collected by the network of Italian association of cancer registries (AIRTUM), provides updated estimates on the incidence risk of multiple primary cancer (MP). The objective is to highlight and quantify the bidirectional associations between different oncological diseases. The quantification of the excess or decreased risk of further cancers in cancer patients, in comparison with the general population, may contribute to understand the aetiology of cancer and to address clinical follow-up.Data herein presented were provided by AIRTUM population-based cancer registries, which cover nowadays 48% of the Italian population. This monograph utilizes the AI…

AdultMaleData Interpretationcancer incidenceAdolescentEpidemiologySettore MED/42 - Igiene Generale E ApplicataNeoplasms Multiple PrimaryCohort StudiesYoung AdultMultiple PrimaryRisk FactorsNeoplasms80 and overHumansChildPreschoolAgedRetrospective StudiesAged 80 and overIncidenceEnvironmental and Occupational Healthmultiple tumourInfantNeoplasms Second Primaryitalian cancer; multiple tumours; cancer incidenceStatisticalMiddle Ageditalian cancerMultiple primary cancer incidenceAdolescent; Adult; Aged; Aged 80 and over; Child; Child Preschool; Cohort Studies; Data Interpretation Statistical; Female; Humans; Incidence; Infant; Italy; Male; Middle Aged; Neoplasms Multiple Primary; Neoplasms Second Primary; Retrospective Studies; Risk Factors; Young AdultSecond PrimaryItalyChild PreschoolData Interpretation StatisticalEpidemiology; Public Health Environmental and Occupational HealthFemalePublic Health
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