Gas chromatographic study of acetyl derivatives of chlorinated 4-hydroxybenzaldehydes

The GC retention times of 4-hydroxybenzaldehyde and its chloro derivatives have been measured on three nonpolar capillary columns. Multiple linear regression analysis has been used to explain the mobility of chlorinated compounds relative to the reference compound 4-hydroxybenzaldehyde. The most important effects have shown to be due to the number of chlorine atoms and the substituents ortho to the formyl group. Other effects have also been observed but found to be unable to explain the GC data.