Modelling of Magnetic Resonance Spectra Using Mixtures for Binned and Truncated Data

2007

Magnetic Resonance Spectroscopy (MRS) provides the biochemical composition of a tissue under study. This information is useful for the in-vivo diagnosis of brain tumours. Prior knowledge of the relative position of the organic compound contributions in the MRS suggests the development of a probabilistic mixture model and its EM-based Maximum Likelihood Estimation for binned and truncated data. Experiments for characterizing and classifying Short Time Echo (STE) spectra from brain tumours are reported.