0000000000632760
AUTHOR
G Parello
Pretreatment quality of life and functional status assessment significantly predict survival of elderly patients with advanced non-small-cell lung cancer receiving chemotherapy: a prognostic analysis of the multicenter Italian lung cancer in the elderly study
Purpose To study the prognostic value for overall survival of baseline assessment of functional status, comorbidity, and quality of life (QoL) in elderly patients with advanced non—small-cell lung cancer treated with chemotherapy. Patients and Methods Data from 566 patients enrolled onto the phase III randomized Multicenter Italian Lung Cancer in the Elderly Study (MILES) study were analyzed. Functional status was measured as activities of daily living (ADL) and instrumental ADL (IADL). The presence of comorbidity was assessed with a checklist of 33 items; items 29 and 30 of the European Organisation for Research and Treatment of Cancer (EORTC) core questionnaire QLQ-C30 (EORTC QLQ-C30) wer…
Unsaturated sand in the stability of the cuesta of the Temple of Hera (Agrigento)
In the Valle dei Templi in Agrigento seven Doric temples stand lengthwise the crest of a rigid calcarenite cuesta over a layer of carbonate sand which lies along a thick stratum of clays. The environment is highly prone to landslides since topplings of calcarenite blocks often occur. The rock slopes are moving back and the slope edge draw near to the foundation of the Temple of Hera Lacinia contributing to increase their perilous condition. To assess the role of unsaturated sands in the instability processes, after the compositional and textural analysis of the material, direct shear tests and oedometer tests have been carried out on sand samples initially at the natural state, with low or …