0000000000636933

AUTHOR

Gerald Blunden

showing 2 related works from this author

Erratum to “Cissampeloflavone, a chalcone–flavone dimer from Cissampelos pareira”[Phytochemistry 64 (2003) 645–647]

2003

ChalconePhytochemistrybiologyStereochemistryDimerPlant ScienceGeneral MedicineHorticulturebiology.organism_classificationBiochemistrychemistry.chemical_compoundchemistryCissampelos pareiraMolecular BiologyPhytochemistry
researchProduct

Cissampeloflavone, a chalcone-flavone dimer from Cissampelos pareira

2003

From the aerial parts of Cissampelos pareira L. (Menispermaceae), a chalcone-flavone dimer has been isolated which, mainly from NMR spectroscopic and MS data, was proved to be 2-(4-hydroxy-3-methoxyphenyl)-7-(4-methoxyphenyl)-6-(2-hydroxy-4,6-dimethoxybenzoyl)-furano[3,2-g]benzopyran-4-one. This has been assigned the trivial name cissampeloflavone. The compound has good activity against Trypanosoma cruzi and T. brucei rhodesiense and has a low toxicity to the human KB cell line.

ChalconeMagnetic Resonance Spectroscopymedicine.drug_classStereochemistryDimerAntiprotozoal AgentsPlant ScienceHorticultureBiologyPharmacognosyBiochemistryFlavonesKB Cellschemistry.chemical_compoundChalconemedicineAnimalsHumansMenispermaceaeTrypanosoma cruziMolecular BiologyFlavonoidschemistry.chemical_classificationEukaryotaGeneral MedicineCissampelosPlant Components Aerialbiology.organism_classificationAntineoplastic Agents PhytogenicchemistryCissampelos pareiraAntiprotozoalDimerizationPhytochemistry
researchProduct