0000000000640282

AUTHOR

Vanessa Saiz-alarcon

showing 2 related works from this author

Involvement of leucocyte/endothelial cell interactions in anorexia nervosa.

2015

Background Anorexia nervosa is a common psychiatric disorder in adolescence and is related to cardiovascular complications. Our aim was to study the effect of anorexia nervosa on metabolic parameters, leucocyte–endothelium interactions, adhesion molecules and proinflammatory cytokines. Materials and Methods This multicentre, cross-sectional, case–control study employed a population of 24 anorexic female patients and 36 controls. We evaluated anthropometric and metabolic parameters, interactions between leucocytes polymorphonuclear neutrophils (PMN) and human umbilical vein endothelial cells (HUVEC), proinflammatory cytokines such as tumour necrosis factor alpha (TNF-α) and interleukin-6 (IL…

Adultmedicine.medical_specialtyAnorexia NervosaAdolescentClinical BiochemistryPopulationInflammationAnorexiaBiochemistrybehavioral disciplines and activitiesBody Mass IndexProinflammatory cytokineYoung AdultleucocytesInternal medicinemental disordersHuman Umbilical Vein Endothelial CellsmedicineHumansCell adhesioneducationInflammationeducation.field_of_studyCell adhesion moleculebusiness.industrydigestive oral and skin physiologyEndothelial CellsGeneral Medicinecytokineslipid profileCross-Sectional StudiesEndocrinologyAnorexia nervosa (differential diagnoses)anorexiaCase-Control StudiesImmunologyLeukocytes MononuclearAdhesionAdhesion anorexia cytokines leucocytes/endothelium interaction lipid profileCytokinesFemaleEndothelium Vascularmedicine.symptombusinessCell Adhesion MoleculesBody mass indexhormones hormone substitutes and hormone antagonistsendothelium interaction
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Altered Mitochondrial Function and Oxidative Stress in Leukocytes of Anorexia Nervosa Patients

2014

ContextAnorexia nervosa is a common illness among adolescents and is characterised by oxidative stress.ObjectiveThe effects of anorexia on mitochondrial function and redox state in leukocytes from anorexic subjects were evaluated.Design and settingA multi-centre, cross-sectional case-control study was performed.PatientsOur study population consisted of 20 anorexic patients and 20 age-matched controls, all of which were Caucasian women.Main outcome measuresAnthropometric and metabolic parameters were evaluated in the study population. To assess whether anorexia nervosa affects mitochondrial function and redox state in leukocytes of anorexic patients, we measured mitochondrial oxygen consumpt…

Anorexia NervosaEating DisordersMitochondrionmedicine.disease_causeBiochemistryElectron Transport Complex IIIchemistry.chemical_compoundLeukocytesMedicine and Health SciencesEnergy-Producing OrganellesMembrane Potential Mitochondrialchemistry.chemical_classificationeducation.field_of_studyMultidisciplinaryQRGlutathioneMitochondriaAnorexia nervosa (differential diagnoses)MedicineFemaleCellular Structures and Organellesmedicine.symptomResearch ArticleAdultmedicine.medical_specialtyAdolescentSciencePopulationContext (language use)AnorexiaBioenergeticsYoung AdultOxygen ConsumptionInternal medicineMental Health and PsychiatrymedicineHumanseducationReactive oxygen speciesElectron Transport Complex Ibusiness.industryBiology and Life SciencesCell BiologyGlutathioneOxidative StressEndocrinologychemistryMitochondrial SizeReactive Oxygen SpeciesbusinessOxidative stressPLoS ONE
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