0000000000643121

AUTHOR

Maria Dolores Perez Carrion

showing 2 related works from this author

ChemInform Abstract: Organocatalytic anti-Selective Mannich Reactions with Fluorinated Aldimines: Synthesis of anti-γ-Fluoroalkyl-γ-amino Alcohols.

2010

The asymmetric Mannich reaction between fluoroalkyl aldimines and aldehydes catalyzed by α,α-diphenylprolinol trimethylsilyl ether is reported. The corresponding Mannich adducts were reduced in situ to afford anti-β-alkyl-γ-fluoroalkyl-γ-amino alcohols in moderate yields and with very high diastereo- and enantioselectivities. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

chemistry.chemical_classificationchemistry.chemical_compoundAldimineTrimethylsilylchemistryOrganic chemistryEtherGeneral MedicineMannich reactionAdductCatalysisChemInform
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Organocatalyticanti-Selective Mannich Reactions with Fluorinated Aldimines: Synthesis ofanti-γ-Fluoroalkyl-γ-amino Alcohols

2009

The asymmetric Mannich reaction between fluoroalkyl aldimines and aldehydes catalyzed by α,α-diphenylprolinol trimethylsilyl ether is reported. The corresponding Mannich adducts were reduced in situ to afford anti-β-alkyl-γ-fluoroalkyl-γ-amino alcohols in moderate yields and with very high diastereo- and enantioselectivities. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

chemistry.chemical_classificationAldimineTrimethylsilylOrganic ChemistryEnantioselective synthesisEtherAldehydeChemical synthesischemistry.chemical_compoundchemistryOrganocatalysisOrganic chemistryPhysical and Theoretical ChemistryMannich reactionEuropean Journal of Organic Chemistry
researchProduct