0000000000643907

AUTHOR

Donata Luiselli

showing 5 related works from this author

Ancient and recent admixture layers in Sicily and Southern Italy trace multiple migration routes along the Mediterranean

2017

The Mediterranean shores stretching between Sicily, Southern Italy and the Southern Balkans witnessed a long series of migration processes and cultural exchanges. Accordingly, present-day population diversity is composed by multiple genetic layers, which make the deciphering of different ancestral and historical contributes particularly challenging. We address this issue by genotyping 511 samples from 23 populations of Sicily, Southern Italy, Greece and Albania with the Illumina GenoChip Array, also including new samples from Albanian-and Greek-speaking ethno-linguistic minorities of Southern Italy. Our results reveal a shared Mediterranean genetic continuity, extending from Sicily to Cypru…

0301 basic medicineMediterranean climateMultidisciplinaryCultural historySouthern Italy Sicily genomic ancestry admxiture Mediterranean populationsScienceBiological anthropologyBiological anthropologyQRSettore BIO/08 - AntropologiaArchaeologyArticle03 medical and health sciences030104 developmental biologyGeographyDNA Sicily Southern Italy Migration routes GenotypingMedicinePopulation diversityGenetic variation
researchProduct

The Greeks in the West: genetic signatures of the Hellenic colonisation in southern Italy and Sicily

2015

Greek colonisation of South Italy and Sicily (Magna Graecia) was a defining event in European cultural history, although the demographic processes and genetic impacts involved have not been systematically investigated. Here, we combine high-resolution surveys of the variability at the uni-parentally inherited Y chromosome and mitochondrial DNA in selected samples of putative source and recipient populations with forward-in-time simulations of alternative demographic models to detect signatures of that impact. Using a subset of haplotypes chosen to represent historical sources, we recover a clear signature of Greek ancestry in East Sicily compatible with the settlement from Euboea during the…

Male0301 basic medicineDIVERSITYPopulation geneticsSicilyPhylogenyGenetics (clinical)POPULATIONGeneticseducation.field_of_studyGeographyGreecehuman population geneticEcologyY-CHROMOSOMEY-CHROMOSOME; POPULATION; ADMIXTURE; LINEAGES; MUTATIONS; DIVERSITY; MODELS; PAIR; TIME; WAVETIMEADMIXTUREFemaleGreeksPopulationMODELSSouth ItalySettore BIO/08 - ANTROPOLOGIABiologyArchaic periodArticleY-CHROMOSOME ; POPULATION ; LINEAGES ; ADMIXTURE ; MUTATIONS ; DIVERSITY ; EXPANSION ; ANCESTOR ; HISTORY ; MODELS03 medical and health sciencesPAIRDemography; Female; Geography; Greece; Haplotypes; Humans; Male; Mutation; Phylogeny; Sicily; Genetics Population; Genetics; Genetics (clinical)GeneticsHumansAncient Greeks population geneticseducationDemographygenetics (clinical); geneticsY chromosomeMUTATIONSHaplotypeLINEAGESpopulation geneticsColonisationGenetics Population030104 developmental biologyHaplotypesGreek ancestryMutationgenetic markersWAVE
researchProduct

Museomics Provides Insights into Conservation and Education:The Instance of an African Lion Specimen from the Museum of Zoology “Pietro Doderlein”

2023

Innovative technological approaches are crucial to enhance naturalistic museum collections and develop information repositories of relevant interest to science, such as threatened animal taxa. In this context, museomics is an emerging discipline that provides a novel approach to the enhancement and exploitation of these collections. In the present study, the discovery of a neglected lion skeleton in the Museum of Zoology “Pietro Doderlein” of the University of Palermo (Italy) offered the opportunity to undertake a multidisciplinary project. The aims of the study consisted of the following: (i) adding useful information for museographic strategies, (ii) obtaining a new genetic data repositor…

Settore L-ART/04 - Museologia E Critica Artistica E Del RestauroeducationlionEcologyEcological ModelingSettore BIO/05 - Zoologiaconservationancient DNA; biodiversity; conservation; digital restoration; education; lion; museomics; museum collections; <i>Panthera leo leo</i>; phylogeographyphylogeographymuseum collectiondigital restorationAgricultural and Biological Sciences (miscellaneous)museomicsmuseomicPanthera leo leoSettore BIO/06 - Anatomia Comparata E Citologiaancient DNAmuseum collectionsNature and Landscape Conservationbiodiversity
researchProduct

Shared language, diverging genetic histories: high-resolution analysis of Y-chromosome variability in Calabrian and Sicilian Arbereshe.

2015

The relationship between genetic and linguistic diversification in human populations has been often explored to interpret some specific issues in human history. The Albanian-speaking minorities of Sicily and Southern Italy (Arbereshe) constitute an important portion of the ethnolinguistic variability of Italy. Their linguistic isolation from neighboring Italian populations and their documented migration history, make such minorities particularly effective for investigating the interplay between cultural, geographic and historical factors. Nevertheless, the extent of Arbereshe genetic relationships with the Balkan homeland and the Italian recipient populations has been only partially investi…

0301 basic medicineMaleGenetics; Genetics (clinical)PopulationY-chromosome variabilityPopulationSettore BIO/08 - ANTROPOLOGIAPopulation geneticsGenetic admixtureHomelandgenetics (clinical)Diversification (marketing strategy)Population stratificationChromosomesArticle03 medical and health sciencesGeneticModelsGenetic variationHumansgeneticseducationLanguageeducation.field_of_studygenetics (clinical); geneticsChromosomes Human YY chromosomeModels GeneticMediterranean Regionpopulation geneticsGenetic Variationlanguage.human_languageY-ChromosomeChromosomes Human Y; Female; Humans; Italy; Male; Mediterranean Region; Pedigree; Population; Genetic Variation; Language; Models GeneticPedigreeHuman Population Genetics Y chromosome Arbereshe linguistic minorities genetic isolates admixture simulations micro-evolutionary history Southern Italy030104 developmental biologyGeographyItalyEvolutionary biologylanguageArbereshe linguistic minorityArbreshFemaleSicilianSicily and CalabriaYHumanEuropean journal of human genetics : EJHG
researchProduct

Global diversity in the TAS2R38 bitter taste receptor: revisiting a classic evolutionary PROPosal

2016

AbstractThe ability to taste phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) is a polymorphic trait mediated by the TAS2R38 bitter taste receptor gene. It has long been hypothesized that global genetic diversity at this locus evolved under pervasive pressures from balancing natural selection. However, recent high-resolution population genetic studies of TAS2Rs suggest that demographic events have played a critical role in the evolution of these genes. We here utilized the largest TAS2R38 database yet analyzed, consisting of 5,589 individuals from 105 populations, to examine natural selection, haplotype frequencies and linkage disequilibrium to estimate the effects of both selectio…

AFRICASELECTION0301 basic medicineLinkage disequilibriumPopulationLocus (genetics)Taste Genetics Evolutionary geneticsBiologyBalancing selectionLinkage DisequilibriumArticleReceptors G-Protein-CoupledEvolution Molecular03 medical and health sciences0302 clinical medicineDatabases GeneticGenetic variationLOCUSHumansPHENYLTHIOCARBAMIDESelection GeneticeducationPOPULATIONVEGETABLESGeneticsGenetic diversityeducation.field_of_studyHUMAN GENETIC DIVERSITY; SENSITIVITY; POPULATION; AFRICA; PTC; PHENYLTHIOCARBAMIDE; VEGETABLES; SELECTION; HUMANS; LOCUSNatural selectionMultidisciplinaryGenetic Variationphenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP)- TAS2R38 haplotypes-natural selectionPhenylthioureaCorrigendaSettore BIO/18 - GeneticaPTC030104 developmental biologyTAS2R38HaplotypesPropylthiouracilTasteHUMAN GENETIC DIVERSITYSENSITIVITY030217 neurology & neurosurgery
researchProduct