0000000000648582

AUTHOR

Jan-malte Sinning

showing 2 related works from this author

Association of Serum Procalcitonin With Cardiovascular Prognosis in Coronary Artery Disease

2011

Background: Procalcitonin (PCT) is an established biomarker for the diagnosis of sepsis. Evidence is growing that PCT concentration correlates with the extent of atherosclerosis and prognosis in patients with coronary artery disease (CAD). Methods and Results: A total of 2,131 patients with CAD were followed up for a median of 3.6 years. During follow-up, death from cardiovascular causes was registered in 95 patients and non-fatal myocardial infarction in 85 patients. Median and quartile 1 and 3 are reported for PCT concentration. Patients who died of cardiovascular causes had higher PCT concentrations [0.021 (0.012/0.036) ng/ml vs. 0.015 (0.010/0.023) ng/ml; P<0.0001]. Patients with acute …

Acute coronary syndromemedicine.medical_specialtyProportional hazards modelbusiness.industryHazard ratioGeneral Medicinemedicine.diseaseConfidence intervalProcalcitoninSurgeryCoronary artery diseaseInternal medicineparasitic diseasesmedicineCardiologyMyocardial infarctionCardiology and Cardiovascular MedicinebusinessSurvival ratehormones hormone substitutes and hormone antagonistsCirculation Journal
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Impact of C-reactive protein and fibrinogen on cardiovascular prognosis in patients with stable angina pectoris: the AtheroGene study.

2006

Aims C-reactive protein and fibrinogen have been extensively studied and shown to be predictive for a first cardiovascular event in healthy individuals. We evaluated the potential clinical use of C-reactive protein and fibrinogen in patients already suffering from coronary artery disease (CAD). Methods and results In a substudy of the prospective Athero Gene registry, we assessed in 1806 patients with documented CAD and stable angina pectoris, the risk of cardiovascular death and non-fatal myocardial infarction ( n =183) over a median follow-up of 3.5 (maximum 7.7) years according to baseline levels of C-reactive protein and fibrinogen. C-reactive protein and fibrinogen were associated with…

Malemedicine.medical_specialtyMyocardial InfarctionFibrinogenDisease-Free SurvivalAngina PectorisCoronary artery diseaseRisk FactorsInternal medicinemedicineHumansIn patientMyocardial infarctionRisk factorbiologybusiness.industryC-reactive proteinConfoundingCoronary StenosisFibrinogenMiddle Agedmedicine.diseasePrognosisC-Reactive ProteinCardiovascular DiseasesCirculatory systembiology.proteinCardiologyFemaleCardiology and Cardiovascular MedicinebusinessBiomarkersmedicine.drugEuropean heart journal
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