0000000000648792

AUTHOR

Francesca Sammartano

showing 3 related works from this author

Treatment of prepubertal periodontitis. A case report and discussion.

1992

Abstract This paper reports the treatment of prepubertal periodontitis in a 3–year-old girl with Papillon-Lefevre Syndrome. Initially, the patient was found to have a myeloperoxidase deficiency and microbiological tests have identified Bacteroides and Fusobacterium, in 60% and 25%, respectively of the total number of microbial flora cultivated. The initial treatment was extraction of all the primary teeth with grade 3 mobility, scaling, root planing and daily subgingival irrigation with a 0.2% solution of chlorhexidine. Several months before the eruption of the first permanent molars, the rest of the primary teeth were extracted. The patient was treated with daily subgingival irrigation of …

MolarPeriodontal pathologyDentistryOral hygieneRoot PlaningPapillon-Lefevre Diseasestomatognathic systemmedicineHumansTooth DeciduousPeriodontitisRest (music)Permanent teethOrthodonticsbiologybusiness.industryChlorhexidineChlorhexidinePubertymedicine.diseasebiology.organism_classificationstomatognathic diseasesFusobacteriumChild PreschoolTooth ExtractionPeriodonticsDental ScalingFemaleBacteroidesbusinessmedicine.drugJournal of clinical periodontology
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Hla-Bb,Dr3 Phenotype and the Antibody Response Against Epstein-Barr Virus

1993

Antibodies against the viral capsid antigen (VCA) and nuclear antigens (EBNAs) of the Epstein-Barr virus (EBV) were determined in a sample of Sicilian population. A significant correlation was observed between HLA-BB,DR3 phenotype and reduced titres of antibodies to EBNAs, whereas HLA-BB,DR3 positive individuals displayed levels of antibodies to VCA comparable to those of HLA-BB,DR3 negative ones. These results further strenghten the suggestion that HLA-BB,DR3 positive subjects are low responders and that the depth of immune response depends on on the fashion of antigenic challenge.

musculoskeletal diseaseseducation.field_of_studyvirusesImmunologyPopulationGeneral MedicineBiologymedicine.disease_causeVirologyEpstein–Barr virusHerpesviridaeVirusSerologyAntigenimmune system diseaseshemic and lymphatic diseasesImmunologyHumoral immunitymedicinebiology.proteinAntibodyeducationImmunological Investigations
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The gene expression profile of cumulus cells reveals altered pathways in patients with endometriosis

2014

PURPOSE: The objective of this experimental study was to compare the global gene expression profile of CC of mature oocytes in 18 patients with severe endometriosis and CC in 18 control patients affected by a severe male factor. METHODS: For each group, the CC were pooled, RNA was extracted and a microarray performed. For validating the microarray, a quantitative real-time PCR was performed in the CC of an independent set of patients with endometriosis (n = 5) and controls (n = 7). RESULTS: 595 differentially expressed genes (320 down-regulated, 275 up-regulated, p < 0.05, fold change ≥1.5) were identified. The most significant changes were observed in genes involved in the chemokine signal…

AdultMaleAdolescentMicroarrayEndometriosisEndometriosisDown-Regulationmacromolecular substancesBiologyBioinformaticsTranscriptomeAndrologyYoung AdultDownregulation and upregulationSettore BIO/13 - Biologia ApplicataGene expressionGeneticsmedicineHumansGenetics (clinical)Cumulus CellsMicroarray analysis techniquesGene Expression Profilingmusculoskeletal neural and ocular physiologygene expression profile cumulus cellObstetrics and GynecologyGeneral Medicinegene expression profile cumulus cells; microarray; EndometriosisMicroarray Analysismedicine.diseaseUp-RegulationGene expression profilingReproductive Physiology and Diseasenervous systemReproductive MedicineCase-Control StudiesOocytesFemaleSignal transductionTranscriptomemicroarraySignal TransductionDevelopmental Biology
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