0000000000649350
AUTHOR
M. Meloni
Low-energy Neutrino Astronomy in LENA
LENA (Low Energy Neutrino Astronomy) is a proposed next-generation neutrino detector based on 50 kilotons of liquid scintillator. The low detection threshold, good energy resolution and excellent background rejection inherent to the liquid-scintillator detectors make LENA a versatile observatory for low-energy neutrinos from astrophysical and terrestrial sources. In the framework of the European LAGUNA-LBNO design study, LENA is also considered as far detector for a very-long baseline neutrino beam from CERN to Pyhasalmi ¨ (Finland). The present contribution gives an overview LENA’s broad research program, highlighting the unique capabilities of liquid scintillator for the detection of low-…
Progression From Paroxysmal to Persistent Atrial Fibrillation. Clinical Correlates and Prognosis
Objectives: We investigated clinical correlates of atrial fibrillation (AF) progression and evaluated the prognosis of patients demonstrating AF progression in a large population. Background: Progression of paroxysmal AF to more sustained forms is frequently seen. However, not all patients will progress to persistent AF. Methods: We included 1,219 patients with paroxysmal AF who participated in the Euro Heart Survey on AF and had a known rhythm status at follow-up. Patients who experienced AF progression after 1 year of follow-up were identified. Results: Progression of AF occurred in 178 (15%) patients. Multivariate analysis showed that heart failure, age, previous transient ischemic attac…
Neutrino Flavor Sensitivity of Large Liquid Scintillator Detectors
Scintillator detectors are known for their good light yield, energy resolution, timing characteristics and pulse shape discrimination capabilities. These features make the next-generation liquid scintillation detector LENA[1] (Low Energy Neutrino Astronomy) the optimal choice for a wide range of astro-particle topics including supernova-, solar-, and geo neutrinos. In addition to the excellent calorimetric and timing properties, scintillartor detectors (LSDs) are also capable of topology reconstruction sufficient to discriminate with adequate efficiency between electron and muon neutrino induced charge current events and neutral current events in the GeV energy range. This feature makes LEN…
Neutrino Flavor Sensitivity of Large Liquid Scintillator Detectors
Abstract Scintillator detectors are known for their good light yield, energy resolution, timing characteristics and pulse shape discrimination capabilities. These features make the next-generation liquid scintillation detector LENA[1] (Low Energy Neutrino Astronomy) the optimal choice for a wide range of astro-particle topics including supernova-, solar-, and geo neutrinos. In addition to the excellent calorimetric and timing properties, scintillartor detectors (LSDs) are also capable of topology reconstruction sufficient to discriminate with adequate efficiency between electron and muon neutrino induced charge current events and neutral current events in the GeV energy range. This feature …
The Italian dementia with Lewy bodies study group (DLB-SINdem): toward a standardization of clinical procedures and multicenter cohort studies design
Dementia with Lewy bodies (DLB) causes elevated outlays for the National Health Systems due to high institutionalization rate and patients' reduced quality of life and high mortality. Furthermore, DLB is often misdiagnosed as Alzheimer's disease. These data motivate harmonized multicenter longitudinal cohort studies to improve clinical management and therapy monitoring. The Italian DLB study group of the Italian Neurological Society for dementia (SINdem) developed and emailed a semi-structured questionnaire to 572 national dementia centers (from primary to tertiary) to prepare an Italian large longitudinal cohort. The questionnaire surveyed: (1) prevalence and incidence of DLB; (2) clinical…