0000000000650320

AUTHOR

Jack Cotter

showing 2 related works from this author

What Is the Role of Dietary Inflammation in Severe Mental Illness? A Review of Observational and Experimental Findings

2019

Severe mental illnesses (SMI), including major depressive disorder, bipolar disorder, and schizophrenia, are associated with increased inflammation. Given diet's role in modulating inflammatory processes, excessive calorie-dense, nutrient-deficient processed food intake may contribute toward the heightened inflammation observed in SMI. This review assesses the evidence from observational and experimental studies to investigate how diet may affect physical and mental health outcomes in SMI through inflammation-related pathways. Cross-sectional studies indicate that individuals with SMI, particularly schizophrenia, consume more pro-inflammatory foods and fewer anti-inflammatory nutrients than…

medicine.medical_specialtylcsh:RC435-571Mini ReviewPopulationnutrition schizophrenia bipolar disorder nutrients vitamin03 medical and health sciences0302 clinical medicinenutrientslcsh:Psychiatrymental disordersmedicineBipolar disorderPsychiatryeducationDepression (differential diagnoses)Psychiatrybipolar disordereducation.field_of_studybusiness.industryvitaminmedicine.diseaseMental illnessMental health3. Good health030227 psychiatryschizophreniaPsychiatry and Mental healthnutritionSchizophreniaMajor depressive disorderObservational studybusiness030217 neurology & neurosurgeryFrontiers in Psychiatry
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The efficacy and safety of nutrient supplements in the treatment of mental disorders: a meta‐review of meta‐analyses of randomized controlled trials

2019

The role of nutrition in mental health is becoming increasingly acknowledged. Along with dietary intake, nutrition can also be obtained from "nutrient supplements", such as polyunsaturated fatty acids (PUFAs), vitamins, minerals, antioxidants, amino acids and pre/probiotic supplements. Recently, a large number of meta-analyses have emerged examining nutrient supplements in the treatment of mental disorders. To produce a meta-review of this top-tier evidence, we identified, synthesized and appraised all meta-analyses of randomized controlled trials (RCTs) reporting on the efficacy and safety of nutrient supplements in common and severe mental disorders. Our systematic search identified 33 me…

eicosapentaenoic acidNutrient supplements polyunsaturated fatty acids omega-3 eicosapentaenoic acid methylfolate vitamin D N-acetylcysteine depression schizophrenia attention-deficit/hyperactivity disorder adjunctive treatmentvitamin Dlaw.invention0302 clinical medicineRandomized controlled triallawL-METHYLFOLATEVITAMIN-D SUPPLEMENTATIONOXIDATIVE STRESSPsychiatryMAJOR DEPRESSIVE DISORDERPOLYUNSATURATED FATTY-ACIDSattention-deficitGUT MICROBIOTAPsychiatry and Mental healthNutrient supplementsCARDIOVASCULAR-DISEASESchizophreniadepressionhyperactivity disorderMajor depressive disorderomega-3Pshychiatric Mental HealthLife Sciences & Biomedicinepolyunsaturated fatty acidsmedicine.medical_specialtyDEFICIT HYPERACTIVITY DISORDERattention-deficit/hyperactivity disorder03 medical and health sciencesmedicineAttention deficit hyperactivity disorderPsychiatryAdverse effectIntensive care medicineScience & Technologybusiness.industrymethylfolateadjunctive treatmentResearch Reportsmedicine.diseaseNUTRITIONAL MEDICINEMental healthN-acetylcysteine030227 psychiatryschizophreniaMood disordersAdjunctive treatmentbusiness030217 neurology & neurosurgeryWorld Psychiatry
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