0000000000652933

AUTHOR

S. Altieri

Evaluation of the Spectroscopic Performance of 3D CZT Drift Strip Detectors

CdTe/CZT is an attractive and consolidated material with which to realize detectors with good efficiency and energy resolution, operating at room temperature and suitable for a large variety of applications such as medical imaging, nuclear security, and astrophysics. Right in this last field several spectro-imagers based on these CdTe/CZT detectors were mounted onboard space missions such as INTEGRAL, Swift, and NuSTAR for hard X and gamma-ray astrophysics. Much effort has been expended in the development of CZT spectroscopic imagers for obtaining sub-millimeter spatial resolution in three dimensions (3D) and high energy resolution up to 1 MeV. The motivations are mainly related to the poss…

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Phenol compounds as new materials for electron spin resonance dosimetry in radiotherapy

Introduction: Among the various dosimetric techniques used for characterizing the radiation beams used in radiation therapy, the electron spin resonance (ESR) arouses increasing interest for applications in various therapy procedures. Free radicals are known to be produced when a compound is irradiated with ionizing radiations. The concentration of radiationinduced free radicals is proportional to the absorbed dose and this allows for dosimetric measurements through ESR technique which enables to quantitatively determine the radical concentration. In this work we report the ESR investigation of phenol pellets and thin films exposed to various types of radiation beams (clinical photon and el…

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CHARACTERIZATION OF THE GAMMA DOSE COMPONENT IN THE NEUTRON FIELD OF A BNCT IRRADIATION FACILITY

At the University of Pavia, a neutron irradiation facility has been constructed for preclinical in vitro and in vivo studies for BNCT. The facility is a wide channel (40 x 20 x 100 cm3) inside the graphite Thermal Column of the 250 KW research reactor TRIGA Mark II. The neutron field consists in a thermal component ranging from about 1010 and 109 cm-2s-1 along the longitudinal axis of the channel and it is uniform within 10% along the transversal axes. The fast neutron contamination (En > 1.58 keV) is more than 2 orders of magnitude lower. The gamma background coming from the core has been reduced with a 20 cm thick bismuth shield, however in the facility a gamma component is still prese…

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Caratterizzazione dosimetrica della facility a neutroni termici del reattore TRIGA di Pavia: studio della dose da fotoni mediante rivelatori ESR di alanina

The optimization of the procedures of Neutron Capture Therapy (NCT) for cancer treatments involves research for beam characterization. One major issue for this therapy is the reliable dosimetric determination of the various (neutronic and photonic) components of the employed beam. In particular, the precise and accurate measurements of the gamma photon component is fundamental for evaluating the risks to healthy tissues hit by the mixed field. Among solid state dosimeters the alanine detectors read by Electron Paramagnetic Resonance (EPR) technique present several advantages such as: tissue equivalence for photon and electron beams, linearity of its dose-response over a wide range, high sta…

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Determinazione della componente gamma nella colone termica del reattore TRIGA di Pavia tramite Dosimetri ESR di alanina

Negli ultimi anni il crescente interesse verso la radioterapia a cattura neutronica (internazionalmente nota come Neutron Capture Therapy - NCT) per il trattamento di neoplasie ha stimolato diverse attività di ricerca finalizzate alla caratterizzazione del fascio utilizzato e all'ottimizzazione delle procedure radioterapiche. Tra i vari sistemi dosimetrici trovano largo impiego i rivelatori a stato solido ESR (Risonanza di Spin Elettronico) a base di alanina che presentano diversi vantaggi come la tessuto equivalenza, la linearità della risposta in un ampio intervallo di dose, l'elevata stabilità dei radicali liberi radioindotti, la non distruttività della lettura del dosimetro e il basso c…

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Determination of gamma component in thermal column of Pavia Triga reactor by using alanine ESR detectors

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Caratterizzazione del campo misto neutroni-gamma nella colonna termica del reattore TRIGA di Pavia tramite attivazione neutronica e rivelatori ad alanina

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High-Resolution 3-D CZT Drift Strip Detectors for Prompt Gamma Ray and Neutron Detection in BNCT

Spectroscopic imagers based on high-Z and wide-bandgap compound semiconductor detectors are widely proposed for the detection of prompt gamma rays in boron neutron capture therapy (BNCT). BNCT is a therapy based on the neutron capture reaction 10B (n,α)7Li. To perform a real-time monitoring of the spatial distribution of 10B during the treatments, the detection of the prompt gamma rays (478 keV), produced by the 7Li recoil nuclei, can be helpful. In this work, we presented the potentialities of new high-resolution CZT drift strip detectors, recently developed by our group, for BNCT measurements. The detectors, exploiting the analysis of the collected-induced charge pulses from anodes, catho…

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