0000000000654925

AUTHOR

L. Fernández-murga

showing 2 related works from this author

The impact of chocolate on cardiovascular health

2011

Cardiovascular disease is the leading determinant of mortality and morbidity in women. Functional foods are attracting interest as potential regulators of the susceptibility to disease. Supported by epidemiological evidence, chocolate has emerged as a possible modulator of cardiovascular risk. Chocolate, or cocoa as the natural source, contains flavanols, a subclass of flavonoids. The latter years have witnessed an increasing number of experimental and clinical studies that suggest a protective effect of chocolate against atherogenesis. Oxidative stress, inflammation, and endothelial function define three biological mechanisms that have shown sensitivity to chocolate. Moreover, the consumpt…

medicine.medical_specialtyFlavonolsmedicine.medical_treatmentCardiovascular healthPhysiologyDiseaseDark chocolateGeneral Biochemistry Genetics and Molecular BiologyfoodFunctional foodFunctional FoodmedicineAnimalsHumansInsulinWhite chocolateInflammationCacaomedicine.diagnostic_testbusiness.industryInsulinObstetrics and GynecologyCardiovascular AgentsPlatelet ActivationLipidsfood.foodSurgeryCardiovascular DiseasesNatural sourceEndothelium VascularPlant PreparationsbusinessLipid profilePhytotherapyMaturitas
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Endometrial response to concurrent treatment with vaginal progesterone and transdermal estradiol.

2012

ABSTRACT Objective To describe the effect of the intermittent administration of vaginal progesterone and a low-dose estradiol patch on endometrial stability, as assessed by the rate of amenorrhea and endometrial stimulation. Methods This was an open study in which 64 moderately symptomatic, postmenopausal women were treated in the outpatient clinic of our University Hospital for different intervals up to 1 year. The treatment consisted of a combination of patches delivering 25 µg/day estradiol and intravaginal pills containing 100 mg of micronized progesterone. Patches and pills were administered concomitantly in a twice-a-week protocol. The endometrial response was assessed by endovaginal …

medicine.medical_specialtyBiopsyEndometriumAdministration CutaneousEndometriumBiopsymedicineOutpatient clinicHumansProgesteroneTransdermalUltrasonographyGynecologymedicine.diagnostic_testEstradiolUterine Hemorrhagebusiness.industryEstrogen Replacement TherapyObstetrics and GynecologyGeneral MedicineMiddle AgedUniversity hospitalPostmenopauseAdministration Intravaginalmedicine.anatomical_structurePillAmenorrheaFemaleUterine Hemorrhagemedicine.symptomAtrophybusinessClimacteric : the journal of the International Menopause Society
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