0000000000658174
AUTHOR
Edvige Di Giovanna
Perfusion MR Imaging in Differentiating High-Grade from Low-Grade Gliomas
To correlate perfusion MR imaging with histologic grade of cerebral gliomas. Materials & Methods Relative cerebral blood volume (rCBV) maps were determined in 22 patients with pathologically proved gliomas (11 glioblastomas, 8 anaplastic gliomas and 2 low-grade gliomas) by dynamic contrast-enhanced T2*-weighted MR imaging. MR examination was completed with conventional T1- and T2-weighted imaging. The rCBV maps were calculated with an independent workstation by fitting a gamma-variate function to the contrast material concentration versus time curve. Relative CBV ratios obtained between tumor and normal white matter were compared between glioblastomas, anaplastic gliomas and low-grade gliom…
Glioma Grading: The Role of Combined Perfusion MR Imaging and Single-Voxel MR Spectroscopy Compared to Conventional MR Imaging
Abstract Body: Purpose To assess the contribution of combined perfusion MR imaging (MRI) and single-voxel MR spectroscopy (MRS) in grading primary gliomas compared with conventional MRI. Materials & Methods Thirty-two patients with primary cerebral glioma underwent conventional MRI, dynamic contrast-enhanced T2*-weighted perfusion MRI and single-voxel proton MRS. Gliomas were graded as low or high based on conventional MRI. The rCBV measurements were obtained from regions of maximum perfusion normalized between tumor and healthy tissue. Metabolite ratios ( [Cho]/[Cr], [Cho]/[NAA], [NAA]/[Cr]) were measured with TE: 34 ms. Tumor grade determined with the three methods then was compared with …
Grading dei gliomi cerebrali: ruolo combinato degli studi RM di perfusione e di spettroscopia a confronto con lo studio in tecnica RM convenzionale
Poster per il 26° Congresso Nazionale Associazione Italiana di Neuroradiologia Diagnostica e Interventistica