0000000000658974

AUTHOR

Francisco Valverde

Applying Conceptual Modeling to Better Understand the Human Genome

The objective of the work is to present the benefits of the application of Conceptual Modeling (CM) in complex domains, such as genomics. This paper explains the evolution of a Conceptual Schema of the Human Genome (CSHG), which seeks to provide a clear and precise understanding of the human genome. We want to highlighting all the advantages of the application of CM in a complex domain such as Genomic Information Systems (GeIS). We show how over time this model has evolved, thus we have discovered better forms of representation. As we advanced in exploring the domain, we understood that we should be extending and incorporating the new concepts detected into our model. Here we present and di…

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Web 2.0 patterns: A model-driven engineering approach

Web Engineering methods, specifically Model-driven Engineering (MDE) ones, are not yet ready to cope with user involvement features that Web 2.0 is demanding. In this work, Web 2.0 patterns are introduced using conceptual models that represent both interaction and functionality, since in Web 2.0 applications both features are intertwined to support the user involvement concern. This work also drafts how Web 2.0 patterns can be integrated into models of a model-driven Web Engineering method.

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A framework to identify primitives that represent usability within Model-Driven Development methods

Context: Nowadays, there are sound methods and tools which implement the Model-Driven Development approach (MDD) satisfactorily. However, MDD approaches focus on representing and generating code that represents functionality, behaviour and persistence, putting the interaction, and more specifically the usability, in a second place. If we aim to include usability features in a system developed with a MDD tool, we need to extend manually the generated code. Objective: This paper tackles how to include functional usability features (usability recommendations strongly related to system functionality) in MDD through conceptual primitives. Method: The approach consists of studying usability guide…

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How to deal with Haplotype data: An Extension to the Conceptual Schema of the Human Genome

[EN] The goal of this work is to describe the advantages of the application of Conceptual Modeling (CM) in complex domains, such as genomics. Nowadays, the study and comprehension of the human genome is a major challenge due to its high level of complexity. The constant evolution in the genomic domain contributes to the generation of ever larger amounts of new data, which means that if we do not manage it correctly data quality could be compromised (i.e., problems related with heterogeneity and inconsistent data). In this paper, we propose the use of a Conceptual Schema of the Human Genome (CSHG), designed to understand and improve our ontological commitment to the domain and also extend (e…

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