Compound Membranes of Linearly Polymerized and Cross-Linked Macrolipids with Phospholipids: Preparation, Microstructure and Applications

Methods for the assembly and for studying the structural and dynamic properties of partially polymerized membranes are described. Mixtures of two classes of polymerizable amphiphiles with diacyl phosphatidylcholines are studied: (1) phosphatidylcholines carrying a diacetylene group per chain (abbreviated as (m,n)-DIINPC (where m + n + 6 equals number of C-Atoms per chain) and (2) a phospholipid-like molecule with a polymerizable methacryl ligand connected to the phosphate head group via (CH2CH2O)m spacers which is abbreviated as (m.n)-POMECY (n = number of C-atoms per chain). — Phase diagrams of the lipid mixtures are established by static light scattering in combination with freeze fractur…