0000000000667034
AUTHOR
Walter J. Hofmann
Complex and Differential Cytokeratin Profiles in Thymomas and Correlation with Normal Thymus
Cytokeratins (CKs) are characterized by highly diverse expression patterns and thus serve as potent epithelial differentiation markers. We have studied 31 cases of thymomas (12 cortical, 2 predominantly cortical, 5 mixed, and 9 medullary type thymomas as well as 3 well-differentiated thymic carcinomas) and, for comparison, 15 normal thymi, for the presence of different CK polypeptides. Immunohistochemistry was performed on cryostat sections using the indirect immunoperoxidase method.
Survival and recurrence after liver transplantation versus liver resection for hepatocellular carcinoma: a retrospective analysis.
Objective This study compares the results of liver transplantation (LTx) and liver resection (LR) for hepatocellular carcinoma (HCC) to test the widespread hypothesis that LTx is the preferable approach for small HCCs. Summary Background Data With respect to scarcity of donor organs and poor results, LTxs for large HCCs are obsolete. Small HCC transplantations have been reported to result in an excellent survival rate. However, the data of comparative studies are controversial. Methods Patients who were treated curatively by LTx (n = 50) or LR (n = 52) for HCC were included in this retrospective study. Survival and freedom from recurrence were analyzed. Patients were stratified according to…