0000000000667326

AUTHOR

Andrew Bell

showing 3 related works from this author

Fluorescence explorer (FLEX): An optimised payload to map vegetation photosynthesis from space

2006

The FLuorescence EXplorer (FLEX) mission proposes to launch a satellite for the global monitoring of steady-state chlorophyll fluorescence in terrestrial vegetation. Fluorescence is a sensitive probe of photosynthetic function in both healthy and physiologically perturbed vegetation, and a powerful non-invasive tool to track the status, resilience, and recovery of photochemical processes and moreover provides important information on overall photosynthetic performance with implications for related carbon sequestration. The early responsiveness of fluorescence to atmospheric, soil and plant water balance, as well as to atmospheric chemistry and human intervention in land usage makes it an ob…

OptimizationEarth observationAtmospheric chemistryAlterra - Centrum Geo-informatieFluorescenceremote sensingLaboratory of Geo-information Science and Remote SensingThree-instrument arrayFLEXLife ScienceLaboratorium voor Geo-informatiekunde en Remote SensingWageningen Environmental ResearchPhotosynthesisSpace researchWater balanceChlorophyll fluorescenceRemote sensingVegetationResiliencePayloadChemistryVegetationCentre Geo-informationPE&RCEarth system scienceFLuorescence EXplorer (FLEX)Space research[SDE]Environmental SciencesEarth (planet)SoilsTerrestrial vegetationSatellite
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Evolution of Seismicity During a Stalled Episode of Reawakening at Cayambe Volcano, Ecuador

2021

Cayambe Volcano is an ice-capped, 5,790 m high, andesitic-dacitic volcanic complex, located on the equator in the Eastern Cordillera of the Ecuadorian Andes. An eruption at Cayambe would pose considerable hazards to surrounding communities and a nationally significant agricultural industry. Although the only historically documented eruption was in 1785, it remains persistently restless and long-period (LP) seismicity has been consistently observed at the volcano for over 10 years. However, the sparse monitoring network, and complex interactions between the magmatic, hydrothermal, glacial, and tectonic systems, make unrest at Cayambe challenging to interpret. In June 2016 a seismic “crisis” …

volcano-tectonic interactionsgeographygeography.geographical_feature_category010504 meteorology & atmospheric sciencesScienceEquatorQvolcano-glacier interactionsInduced seismicityFault (geology)010502 geochemistry & geophysics01 natural sciencesTectonicsVolcanoMagmavolcano-seismic swarmsGeneral Earth and Planetary SciencesGlacial periodlong-period seismicityVolcanic coneGeologySeismology0105 earth and related environmental sciencesvolcanic monitoringFrontiers in Earth Science
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An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs.

2021

[BACKGROUND & AIMS] Primary biliary cholangitis (PBC) is a chronic liver disease in which autoimmune destruction of the small intra-hepatic bile ducts eventually leads to cirrhosis. Many patients have inadequate response to licensed medications, motivating the search for novel therapies. Previous genome-wide association studies (GWAS) and meta-analyses (GWMA) of PBC have identified numerous risk loci for this condition, providing insight into its aetiology. We undertook the largest GWMA of PBC to date, aiming to identify additional risk loci and prioritise candidate genes for in silico drug efficacy screening. [METHODS] We combined new and existing genotype data for 10, 516 cases and 20, 77…

Liver CirrhosisALSPAC; ERN RARE-LIVER; Genomic co-localization; Network-based in silico drug efficacy screening; UK-PBC0301 basic medicineCandidate geneALSPAC; ERN RARE-LIVER; Genomic co-localization; Network-based in silico drug efficacy screening; UK-PBC; Genome-Wide Association Study; Humans; Liver Cirrhosis BiliaryItalian PBC Study GroupLD SCORE REGRESSIONJapan-PBC-GWAS ConsortiumGenome-wide association studyLocus (genetics)DiseaseSUSCEPTIBILITYPBCChronic liver diseaseBioinformaticsGENETIC ASSOCIATION1117 Public Health and Health Services03 medical and health sciences0302 clinical medicineUK-PBC ConsortiumGenotypeHumansMedicineNetwork-based in silico drug efficacy screeningGenetic associationScience & TechnologyGastroenterology & HepatologyHepatologyLiver Cirrhosis Biliarybusiness.industryBiliaryChinese PBC Consortium1103 Clinical SciencesALSPACmedicine.diseasePBC Consortia030104 developmental biologyMeta-analysisERN RARE LIVER030211 gastroenterology & hepatologyGenomic co-localizationUK-PBCUS PBC ConsortiumERN RARE-LIVERCanadian PBC ConsortiumbusinessLife Sciences & BiomedicineGenome-Wide Association StudyHuman
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