0000000000672755

AUTHOR

David J.a. Jenkins

showing 2 related works from this author

Continuous therapy with transdermal nitroglycerin does not affect biomarkers of vascular inflammation and injury in healthy volunteers.

2009

Continuous exposure to nitroglycerin (GTN) results in development of tolerance and is associated with increased free radical production and abnormal endothelial function. Elevated plasma biomarkers of inflammation have been shown to be associated with endothelial dysfunction in most cardiovascular conditions. It remains unclear whether exposure to GTN is also associated with increased biomarkers of endothelial and vascular injury or vascular inflammation. In an investigator-blind study, a total of 28 healthy volunteers were randomized to continuous therapy with GTN (0.6 mg/h 24 h/day for 7 days) or no therapy. Venous blood was collected on day 0 and day 7. Plasma levels of markers such as …

AdultMaleVasculitisTime FactorsEndotheliumAdolescentPhysiologyVasodilator AgentsInflammationPharmacologyAdministration CutaneousArginineLesionNitroglycerinYoung AdultPhysiology (medical)MedicineHumansEndothelial dysfunctionTransdermalPharmacologyDose-Response Relationship Drugbusiness.industryInterleukin-6Tumor Necrosis Factor-alphaGeneral MedicineVenous bloodmedicine.diseaseLipoproteins LDLDose–response relationshipP-Selectinmedicine.anatomical_structureAnesthesiacardiovascular systemTumor necrosis factor alphaEndothelium Vascularmedicine.symptombusinessCell Adhesion MoleculesBiomarkerscirculatory and respiratory physiologyCanadian journal of physiology and pharmacology
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Dietary Glycaemic Index Labelling: A Global Perspective

2021

The glycaemic index (GI) is a food metric that ranks the acute impact of available (digestible) carbohydrates on blood glucose. At present, few countries regulate the inclusion of GI on food labels even though the information may assist consumers to manage blood glucose levels. Australia and New Zealand regulate GI claims as nutrition content claims and also recognize the GI Foundation’s certified Low GI trademark as an endorsement. The GI Foundation of South Africa endorses foods with low, medium and high GI symbols. In Asia, Singapore’s Healthier Choice Symbol has specific provisions for low GI claims. Low GI claims are also permitted on food labels in India. In China, there are no nation…

TrademarkHarmonizationReviewCertificationGlobal HealthBest interestsGlycaemic indexFood LabelingLabellingEnvironmental healthparasitic diseasesHumansmedia_common.cataloged_instanceTX341-641European unionmedia_commonNutrition and DieteticsdiabetesNutrition. Foods and food supplysocial sciencesDietfood regulationFood regulationGlycemic Indexglycaemic indexpopulation characteristicsBusinesshuman activitiesFood Analysisfood labelsgeographic locationsFood ScienceNutrients
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