0000000000675379

AUTHOR

R Sirchia

showing 2 related works from this author

Type V collagen and protein kinase C η down-regulation in 8701-BC breast cancer cells.

2011

We previously reported that ductal infiltrating carcinomas (d.i.c.) of the human breast display profound modifications of the stromal architecture, associated with anomalous collagen composition. Among the major alterations observed in the interstitial collagen, the relative increase of type V collagen content was detected. When type V collagen was used as an ‘‘in vitro’’ substrate for 8701-BC d.i.c. cells, it appeared able to restrain cell growth, inhibit cell motility and invasion ‘‘in vitro’’, and modify the expression levels of genes coding for apoptosis factors, caspases and stress response proteins. In the present paper we demonstrate that type V collagen induces the down-regulation o…

Caspase 8bcl-X ProteinDown-RegulationApoptosisBreast NeoplasmsDNA FragmentationOligonucleotides AntisenseGene Expression Regulation NeoplasticIsoenzymesCaspasesCell Line TumorHumansFemalebcl-Associated Death ProteinSettore BIO/06 - Anatomia Comparata E CitologiaCollagen Type Vdifferential display protein kinase breast cancer gene expression collagenProtein Kinase CCell ProliferationMolecular carcinogenesis
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Effect of cadmium and manganese on gene expression and “in vitro” proliferative and invasive behaviour of MDA-MB231 human breast cancer cells

2009

manganese breast cancer cellcell proliferationcadmiumcadmium manganese breast cancer proliferation invasionSettore BIO/06 - Anatomia Comparata E Citologiacell invasion
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