Author: J.l. Mazet

0000000000675730

AUTHOR

J.l. Mazet

Combination of the novel farnesyltransferase inhibitor RPR 130401 and the gerannylgeranyltransferase-1 inhibitor GGTI-298 disrupts MAP kinase activation and G1-S transition in Ki-Ras-overexpressing transformed adrenocortical cells

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research product

Geranylgeranyl as well as farnesyl moiety is transferred to Ras p21 overproduced in adrenocortical cells transformed by c-Ha-ras oncogene

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